A cryptic tubulin-binding domain links MEKK1 to curved tubulin protomers

The MEKK1 protein is a pivotal kinase activator of responses to cellular stress. Activation of MEKK1 can trigger various responses, including mitogen-activated protein (MAP) kinases, NF-κB signaling, or cell migration. Notably, MEKK1 activity is triggered by microtubule-targeting chemotherapies, amo...

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Detalles Bibliográficos
Autores principales: Filipčík, Pavel, Latham, Sharissa L., Cadell, Antonia L., Day, Catherine L., Croucher, David R., Mace, Peter D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474687/
https://www.ncbi.nlm.nih.gov/pubmed/32817551
http://dx.doi.org/10.1073/pnas.2006429117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474687/
https://www.ncbi.nlm.nih.gov/pubmed/32817551
http://dx.doi.org/10.1073/pnas.2006429117

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