Cargando…

Mesenchymal Stromal Cells Suppress Hippocampal Neuron Autophagy Stress Induced by Hypoxic-Ischemic Brain Damage: The Possible Role of Endogenous IL-6 Secretion

BACKGROUND: Increasing evidence has revealed that mesenchymal stromal cell (MSC) transplantation alleviates hypoxic-ischemic brain damage (HIBD) induced neurological impairments via immunomodulating astrocyte antiapoptosis effects. However, it remains unclear whether MSCs regulate neuron autophagy f...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Miao, Sun, Wuqing, Xiao, Lu, He, Mulan, Gu, Yan, Yang, Ting, Chen, Jie, Liang, Xiaohua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474748/ https://www.ncbi.nlm.nih.gov/pubmed/32908484 http://dx.doi.org/10.1155/2020/8822579

Ejemplares similares

Endogenous IL-6 of mesenchymal stem cell improves behavioral outcome of hypoxic-ischemic brain damage neonatal rats by supressing apoptosis in astrocyte
por: Gu, Yan, et al.
Publicado: (2016)

Research advances in the role of endogenous neurogenesis on neonatal hypoxic-ischemic brain damage
por: Chen, Andi, et al.
Publicado: (2022)

Cognitive Dysfunction and Hippocampal Damage Induced by Hypoxic-Ischemic Brain Injury and Prolonged Febrile Convulsions in Immature Rats
por: Byeon, Jung Hye, et al.
Publicado: (2015)

Peptidomic Analysis of Neonate Umbilical Cord Blood for the Identification of Endogenous Peptides Involved in Hypoxic–Ischemic Encephalopathy
por: Dong, Xiaohua, et al.
Publicado: (2021)

New possibilities for neuroprotection in neonatal hypoxic-ischemic encephalopathy
por: Victor, Suresh, et al.
Publicado: (2021)

Effect of mild hypothermia on the expression of IL-10 and IL-18 in neonates with hypoxic ischemic encephalopathy
por: Wu, Hongwei, et al.
Publicado: (2019)

Neuroprotective Mechanism of Icariin on Hypoxic Ischemic Brain Damage in Neonatal Mice
por: Wang, Mengxia, et al.
Publicado: (2022)

Measurement of thalamus and cortical damages in hypoxic ischemic encephalopathy
por: Sohn, GyeongMo, et al.
Publicado: (2023)

Circadian Profile of Salivary Melatonin Secretion in Hypoxic Ischemic Encephalopathy
por: Kapek, Łukasz, et al.
Publicado: (2020)

NF-κB signaling pathway inhibition suppresses hippocampal neuronal apoptosis and cognitive impairment via RCAN1 in neonatal rats with hypoxic-ischemic brain damage
por: Fang, Hua, et al.
Publicado: (2019)

Heart rate variability as possible marker of brain damage in neonates with hypoxic ischemic encephalopathy: a systematic review
por: Bersani, Iliana, et al.
Publicado: (2020)

Preventing Brain Damage from Hypoxic–Ischemic Encephalopathy in Neonates: Update on Mesenchymal Stromal Cells and Umbilical Cord Blood Cells
por: Nabetani, Makoto, et al.
Publicado: (2021)

Thiamine as a Possible Neuroprotective Strategy in Neonatal Hypoxic-Ischemic Encephalopathy
por: Sechi, Gian Pietro, et al.
Publicado: (2021)

Reduced Hippocampal Volumes in Children with History of Hypoxic Ischemic Encephalopathy after Therapeutic Hypothermia
por: Pfister, Katie M., et al.
Publicado: (2023)

Perinatal Hypoxic-Ischemic Encephalopathy
por: Lai, Ming-Chi, et al.
Publicado: (2011)

Hydrogen water reduces NSE, IL-6, and TNF-α levels in hypoxic-ischemic encephalopathy
por: Yang, Lin, et al.
Publicado: (2016)

Peptidome analysis of cerebrospinal fluid in neonates with hypoxic-ischemic brain damage
por: Hou, Xuewen, et al.
Publicado: (2020)

Clinical Implications of Epigenetic Dysregulation in Perinatal Hypoxic-Ischemic Brain Damage
por: Bustelo, Martín, et al.
Publicado: (2020)

Resatorvid protects against hypoxic-ischemic brain damage in neonatal rats
por: Jiang, Li-Jun, et al.
Publicado: (2020)

Immunomodulatory Mechanism and Potential Therapies for Perinatal Hypoxic-Ischemic Brain Damage
por: Min, Ying-Jun, et al.
Publicado: (2020)

Possible modulatory effect of endogenous islet catecholamines on insulin secretion
por: Borelli, Maria I, et al.
Publicado: (2001)

MiR-127-3p targeting CISD1 regulates autophagy in hypoxic–ischemic cortex
por: Zhang, Zi-Bin, et al.
Publicado: (2021)

The role of pineal microRNA-325 in regulating circadian rhythms after neonatal hypoxic-ischemic brain damage
por: Sha, Ning, et al.
Publicado: (2021)

Diffusion kurtosis imaging and pathological comparison of early hypoxic–ischemic brain damage in newborn piglets
por: Xiao, Juan, et al.
Publicado: (2020)

Expression profile of circular RNAs in the peripheral blood of neonates with hypoxic-ischemic encephalopathy
por: Dong, Xiaohua, et al.
Publicado: (2020)

Ginsenoside-Rb1 Protects Hypoxic- and Ischemic-Damaged Cardiomyocytes by Regulating Expression of miRNAs
por: Yan, Xu, et al.
Publicado: (2015)

Dedifferentiated human umbilical cord mesenchymal stem cell reprogramming of endogenous hSDF-1α expression participates in neural restoration in hypoxic-ischemic brain damage rats
por: Xiaoqin, Zhou, et al.
Publicado: (2020)

Intranasal Delivery of Mesenchymal Stromal Cells Protects against Neonatal Hypoxic–Ischemic Brain Injury
por: McDonald, Courtney A., et al.
Publicado: (2019)

Delayed onset hypokinetic-rigid syndrome due to hypoxic-ischemic damage of the striatum
por: Moudrous, Walid, et al.
Publicado: (2016)

Early predictors of brain damage in full-term newborns with hypoxic ischemic encephalopathy
por: Alkholy, Usama M, et al.
Publicado: (2017)

Comparison of the Effects of Citicoline and Piracetam on Hypoxic-ischemic Brain Damage in Neonatal Rabbits
por: EBRAHIMI, Sedigheh, et al.
Publicado: (2022)

Gallic acid inhibits neuroinflammation and reduces neonatal hypoxic-ischemic brain damages
por: Dong, Xiangjun, et al.
Publicado: (2022)

Lipocortin-1 is an endogenous inhibitor of ischemic damage in the rat brain
Publicado: (1991)

Effects of progesterone on hippocampal ultrastructure and expression of inflammatory mediators in neonatal rats with hypoxic-ischemic brain injury
por: LI, XIAOJUAN, et al.
Publicado: (2014)

Neuroprotective effect of astrocyte-derived IL-33 in neonatal hypoxic-ischemic brain injury
por: Jiao, Mengya, et al.
Publicado: (2020)

Deciding what is possible and impossible following hippocampal damage in humans
por: McCormick, Cornelia, et al.
Publicado: (2017)

Retraction: Reduction of neuronal damage and promotion of locomotor recovery after spinal cord injury by early administration of methylprednisolone: possible involvement of autophagy pathway
por: Jin, Yichao, et al.
Publicado: (2022)

MicroRNA-9 mediated the protective effect of ferulic acid on hypoxic-ischemic brain damage in neonatal rats
por: Yao, Keli, et al.
Publicado: (2020)

Human pluripotent stem cell-derived ectomesenchymal stromal cells promote more robust functional recovery than umbilical cord-derived mesenchymal stromal cells after hypoxic-ischaemic brain damage
por: Huang, Jiawei, et al.
Publicado: (2022)

Protective effects on acute hypoxic-ischemic brain damage in mfat-1 transgenic mice by alleviating neuroinflammation
por: Geng, Xue, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_cq4r3ljbeshnenn3soub5l6tmj