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Radiographic and clinical neurologic manifestations of COVID-19 related hypoxemia

The novel coronavirus SARS-CoV-2 is known to cause hypoxemia and acute respiratory distress syndrome (ARDS) in a significant portion of those with severe disease. Survivors of critical illness and ARDS often experience neurocognitive impairment but, to date, there is scant literature correlating rad...

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Detalles Bibliográficos
Autores principales: Radnis, Caitlin, Qiu, Sunny, Jhaveri, Miral, Da Silva, Ivan, Szewka, Aimee, Koffman, Lauren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474836/
https://www.ncbi.nlm.nih.gov/pubmed/32957036
http://dx.doi.org/10.1016/j.jns.2020.117119
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author Radnis, Caitlin
Qiu, Sunny
Jhaveri, Miral
Da Silva, Ivan
Szewka, Aimee
Koffman, Lauren
author_facet Radnis, Caitlin
Qiu, Sunny
Jhaveri, Miral
Da Silva, Ivan
Szewka, Aimee
Koffman, Lauren
author_sort Radnis, Caitlin
collection PubMed
description The novel coronavirus SARS-CoV-2 is known to cause hypoxemia and acute respiratory distress syndrome (ARDS) in a significant portion of those with severe disease. Survivors of critical illness and ARDS often experience neurocognitive impairment but, to date, there is scant literature correlating radiographic hypoxic brain injury to hypoxemia related to ARDS. In this case series, we describe three cases of hypoxic brain injury seen on magnetic resonance imaging (MRI) in patients with hypoxemia secondary to COVID-19-related ARDS. The lack of severe observed hypoxemia in two of the cases suggests that unrecognized or asymptomatic hypoxemia may play a role in hypoxic brain injury related to COVID-19.
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spelling pubmed-74748362020-09-08 Radiographic and clinical neurologic manifestations of COVID-19 related hypoxemia Radnis, Caitlin Qiu, Sunny Jhaveri, Miral Da Silva, Ivan Szewka, Aimee Koffman, Lauren J Neurol Sci Clinical Short Communication The novel coronavirus SARS-CoV-2 is known to cause hypoxemia and acute respiratory distress syndrome (ARDS) in a significant portion of those with severe disease. Survivors of critical illness and ARDS often experience neurocognitive impairment but, to date, there is scant literature correlating radiographic hypoxic brain injury to hypoxemia related to ARDS. In this case series, we describe three cases of hypoxic brain injury seen on magnetic resonance imaging (MRI) in patients with hypoxemia secondary to COVID-19-related ARDS. The lack of severe observed hypoxemia in two of the cases suggests that unrecognized or asymptomatic hypoxemia may play a role in hypoxic brain injury related to COVID-19. Elsevier B.V. 2020-11-15 2020-09-06 /pmc/articles/PMC7474836/ /pubmed/32957036 http://dx.doi.org/10.1016/j.jns.2020.117119 Text en © 2020 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Clinical Short Communication
Radnis, Caitlin
Qiu, Sunny
Jhaveri, Miral
Da Silva, Ivan
Szewka, Aimee
Koffman, Lauren
Radiographic and clinical neurologic manifestations of COVID-19 related hypoxemia
title Radiographic and clinical neurologic manifestations of COVID-19 related hypoxemia
title_full Radiographic and clinical neurologic manifestations of COVID-19 related hypoxemia
title_fullStr Radiographic and clinical neurologic manifestations of COVID-19 related hypoxemia
title_full_unstemmed Radiographic and clinical neurologic manifestations of COVID-19 related hypoxemia
title_short Radiographic and clinical neurologic manifestations of COVID-19 related hypoxemia
title_sort radiographic and clinical neurologic manifestations of covid-19 related hypoxemia
topic Clinical Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474836/
https://www.ncbi.nlm.nih.gov/pubmed/32957036
http://dx.doi.org/10.1016/j.jns.2020.117119
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