Emergence and evolution of highly pathogenic porcine epidemic diarrhea virus by natural recombination of a low pathogenic vaccine isolate and a highly pathogenic strain in the spike gene

Outbreaks of a new variant of porcine epidemic diarrhea virus (PEDV) at the end of 2010 have raised interest in the mutation and recombination of PEDV. A PEDV strain (CN/Liaoning25/2018) isolated from a clinical outbreak of piglet diarrhea contained a 49-bp deletion in the ORF3 gene. This deletion i...

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Detalles Bibliográficos
Autores principales: Wang, Huinan, Zhang, Libo, Shang, Yuanbin, Tan, Rongrong, Ji, Mingxiang, Yue, Xinliang, Wang, Nannan, Liu, Jun, Wang, Chunhua, Li, Yonggang, Zhou, Tiezhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474927/
https://www.ncbi.nlm.nih.gov/pubmed/32913664
http://dx.doi.org/10.1093/ve/veaa049

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