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Fatal Fulminant Legionnaires' Disease in a Patient on Maintenance Hemodialysis

We herein report a case of fulminant Legionnaires' disease with autopsy findings in a patient on maintenance hemodialysis (HD). Chronic kidney disease is a strong risk factor for Legionnaires' disease, although there have been only a few reports in HD patients. Because most patients on HD...

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Detalles Bibliográficos
Autores principales: Kawashima, Akira, Katagiri, Daisuke, Kondo, Isao, Sakamoto, Emi, Suzuki, Minami, Arai, Yohei, Sato, Fumie, Tada, Manami, Hinoshita, Fumihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474993/
https://www.ncbi.nlm.nih.gov/pubmed/32321897
http://dx.doi.org/10.2169/internalmedicine.4530-20
Descripción
Sumario:We herein report a case of fulminant Legionnaires' disease with autopsy findings in a patient on maintenance hemodialysis (HD). Chronic kidney disease is a strong risk factor for Legionnaires' disease, although there have been only a few reports in HD patients. Because most patients on HD are anuric, the use of rapid assay kits to detect antigens in urine samples for the diagnosis of Legionnaires' disease is not always feasible. We suggest the use of clinical predictive tools or the loop-mediated isothermal amplification (LAMP) method, which can be applied for anuric patients, such as those on HD, with pneumonia.