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New Methods to Calculate Concordance Factors for Phylogenomic Datasets
We implement two measures for quantifying genealogical concordance in phylogenomic data sets: the gene concordance factor (gCF) and the novel site concordance factor (sCF). For every branch of a reference tree, gCF is defined as the percentage of “decisive” gene trees containing that branch. This me...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7475031/ https://www.ncbi.nlm.nih.gov/pubmed/32365179 http://dx.doi.org/10.1093/molbev/msaa106 |
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author | Minh, Bui Quang Hahn, Matthew W Lanfear, Robert |
author_facet | Minh, Bui Quang Hahn, Matthew W Lanfear, Robert |
author_sort | Minh, Bui Quang |
collection | PubMed |
description | We implement two measures for quantifying genealogical concordance in phylogenomic data sets: the gene concordance factor (gCF) and the novel site concordance factor (sCF). For every branch of a reference tree, gCF is defined as the percentage of “decisive” gene trees containing that branch. This measure is already in wide usage, but here we introduce a package that calculates it while accounting for variable taxon coverage among gene trees. sCF is a new measure defined as the percentage of decisive sites supporting a branch in the reference tree. gCF and sCF complement classical measures of branch support in phylogenetics by providing a full description of underlying disagreement among loci and sites. An easy to use implementation and tutorial is freely available in the IQ-TREE software package (http://www.iqtree.org/doc/Concordance-Factor, last accessed May 13, 2020). |
format | Online Article Text |
id | pubmed-7475031 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-74750312020-09-10 New Methods to Calculate Concordance Factors for Phylogenomic Datasets Minh, Bui Quang Hahn, Matthew W Lanfear, Robert Mol Biol Evol Methods We implement two measures for quantifying genealogical concordance in phylogenomic data sets: the gene concordance factor (gCF) and the novel site concordance factor (sCF). For every branch of a reference tree, gCF is defined as the percentage of “decisive” gene trees containing that branch. This measure is already in wide usage, but here we introduce a package that calculates it while accounting for variable taxon coverage among gene trees. sCF is a new measure defined as the percentage of decisive sites supporting a branch in the reference tree. gCF and sCF complement classical measures of branch support in phylogenetics by providing a full description of underlying disagreement among loci and sites. An easy to use implementation and tutorial is freely available in the IQ-TREE software package (http://www.iqtree.org/doc/Concordance-Factor, last accessed May 13, 2020). Oxford University Press 2020-05-04 /pmc/articles/PMC7475031/ /pubmed/32365179 http://dx.doi.org/10.1093/molbev/msaa106 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Methods Minh, Bui Quang Hahn, Matthew W Lanfear, Robert New Methods to Calculate Concordance Factors for Phylogenomic Datasets |
title | New Methods to Calculate Concordance Factors for Phylogenomic Datasets |
title_full | New Methods to Calculate Concordance Factors for Phylogenomic Datasets |
title_fullStr | New Methods to Calculate Concordance Factors for Phylogenomic Datasets |
title_full_unstemmed | New Methods to Calculate Concordance Factors for Phylogenomic Datasets |
title_short | New Methods to Calculate Concordance Factors for Phylogenomic Datasets |
title_sort | new methods to calculate concordance factors for phylogenomic datasets |
topic | Methods |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7475031/ https://www.ncbi.nlm.nih.gov/pubmed/32365179 http://dx.doi.org/10.1093/molbev/msaa106 |
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