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Prebiotic administration modulates gut microbiota and faecal short-chain fatty acid concentrations but does not prevent chronic intermittent hypoxia-induced apnoea and hypertension in adult rats

BACKGROUND: Evidence is accruing to suggest that microbiota-gut-brain signalling plays a regulatory role in cardiorespiratory physiology. Chronic intermittent hypoxia (CIH), modelling human sleep apnoea, affects gut microbiota composition and elicits cardiorespiratory morbidity. We investigated if t...

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Detalles Bibliográficos
Autores principales:	O'Connor, Karen M., Lucking, Eric F., Bastiaanssen, Thomaz F.S., Peterson, Veronica L., Crispie, Fiona, Cotter, Paul D., Clarke, Gerard, Cryan, John F., O'Halloran, Ken D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Research paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7475129/ https://www.ncbi.nlm.nih.gov/pubmed/32861200 http://dx.doi.org/10.1016/j.ebiom.2020.102968

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