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A defucosylated anti-PD-L1 monoclonal antibody 13-mG(2a)-f exerts antitumor effects in mouse xenograft models of oral squamous cell carcinoma
Programmed cell death ligand-1 (PD-L1) is a type I transmembrane glycoprotein expressed on antigen-presenting cells and several tumor cells, including melanoma and lung cancer cells. A strong correlation has been reported between PD-L1 expression in tumor cells and negative prognosis in cancer patie...
Autores principales: | Takei, Junko, Ohishi, Tomokazu, Kaneko, Mika K., Harada, Hiroyuki, Kawada, Manabu, Kato, Yukinari |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7475192/ https://www.ncbi.nlm.nih.gov/pubmed/32923698 http://dx.doi.org/10.1016/j.bbrep.2020.100801 |
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