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A defucosylated anti-PD-L1 monoclonal antibody 13-mG(2a)-f exerts antitumor effects in mouse xenograft models of oral squamous cell carcinoma

Programmed cell death ligand-1 (PD-L1) is a type I transmembrane glycoprotein expressed on antigen-presenting cells and several tumor cells, including melanoma and lung cancer cells. A strong correlation has been reported between PD-L1 expression in tumor cells and negative prognosis in cancer patie...

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Detalles Bibliográficos
Autores principales: Takei, Junko, Ohishi, Tomokazu, Kaneko, Mika K., Harada, Hiroyuki, Kawada, Manabu, Kato, Yukinari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7475192/
https://www.ncbi.nlm.nih.gov/pubmed/32923698
http://dx.doi.org/10.1016/j.bbrep.2020.100801

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