Cargando…

Fluorophore-conjugated Helicobacter pylori recombinant membrane protein (HopQ) labels primary colon cancer and metastases in orthotopic mouse models by binding CEA-related cell adhesion molecules

HopQ is an outer-membrane protein of Helicobacter pylori that binds to human carcinoembryonic antigen-related cell-adhesion molecules (CEACAMs) with high specificity. We aimed to investigate fluorescence targeting of CEACAM-expressing colorectal tumors in patient-derived orthotopic xenograft (PDOX)...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hollandsworth, Hannah M., Schmitt, Verena, Amirfakhri, Siamak, Filemoni, Filemoni, Schmidt, Alexej, Landström, Maréne, Lyndin, Mykola, Backert, Steffen, Gerhard, Markus, Wennemuth, Gunther, Hoffman, Robert M., Singer, Bernhard B., Bouvet, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2020
Materias:	Original article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7475271/ https://www.ncbi.nlm.nih.gov/pubmed/32866936 http://dx.doi.org/10.1016/j.tranon.2020.100857

Ejemplares similares

Anti-carcinoembryonic antigen-related cell adhesion molecule antibody for fluorescence visualization of primary colon cancer and metastases in patient-derived orthotopic xenograft mouse models
por: Hollandsworth, Hannah M., et al.
Publicado: (2020)

Near-infrared photoimmunotherapy is effective treatment for colorectal cancer in orthotopic nude-mouse models
por: Hollandsworth, Hannah M., et al.
Publicado: (2020)

Fluorescent humanized anti-CEA antibody specifically labels metastatic pancreatic cancer in a patient-derived orthotopic xenograft (PDOX) mouse model
por: Lwin, Thinzar M., et al.
Publicado: (2018)

Cysteine Residues in Helicobacter pylori Adhesin HopQ Are Required for CEACAM–HopQ Interaction and Subsequent CagA Translocation
por: Hamway, Youssef, et al.
Publicado: (2020)

Monocytes engineered with iSNAP inhibit human B‐lymphoma progression
por: Wu, Haohsiang, et al.
Publicado: (2022)

Effects of Helicobacter pylori adhesin HopQ binding to CEACAM receptors in the human stomach
por: Nguyen, Quynh Anh, et al.
Publicado: (2023)

The HopQ-CEACAM Interaction Controls CagA Translocation, Phosphorylation, and Phagocytosis of Helicobacter pylori in Neutrophils
por: Behrens, Ina-Kristin, et al.
Publicado: (2020)

Fluorescent Anti-CEA Nanobody for Rapid Tumor-Targeting and Imaging in Mouse Models of Pancreatic Cancer
por: Lwin, Thinzar M., et al.
Publicado: (2022)

The Use of Fluorescent Anti-CEA Antibodies to Label, Resect and Treat Cancers: A Review
por: Turner, Michael A., et al.
Publicado: (2021)

Engagement of CEACAM1 by Helicobacter pylori HopQ Is Important for the Activation of Non-Canonical NF-κB in Gastric Epithelial Cells
por: Taxauer, Karin, et al.
Publicado: (2021)

High Prevalence of Helicobacter pylori hopQ II Genotype Isolated from Iranian Patients with Gastroduodenal Disorders
por: Talebi Bezmin Abadi, Amin, et al.
Publicado: (2014)

Proof of Principle of Combining Fluorescence-Guided Surgery with Photoimmunotherapy to Improve the Outcome of Pancreatic Cancer Therapy in an Orthotopic Mouse Model
por: Nishino, Hiroto, et al.
Publicado: (2022)

Two Strategies of Pseudomonas syringae to Avoid Recognition of the HopQ1 Effector in Nicotiana Species
por: Zembek, Patrycja, et al.
Publicado: (2018)

Novel Sensitive Electrochemical Immunosensor Development for the Selective Detection of HopQ H. pylori Bacteria Biomarker
por: Jaradat, Hussamaldeen, et al.
Publicado: (2023)

Bacterial type III effector protein HopQ inhibits melanoma motility through autophagic degradation of vimentin
por: Park, Seung-Ho, et al.
Publicado: (2020)

Pathogenic interactions between Helicobacter pylori adhesion protein HopQ and human cell surface adhesion molecules CEACAMs in gastric epithelial cells
por: Xia, Ran, et al.
Publicado: (2019)

The HopQ1 Effector’s Nucleoside Hydrolase-Like Domain Is Required for Bacterial Virulence in Arabidopsis and Tomato, but Not Host Recognition in Tobacco
por: Li, Wei, et al.
Publicado: (2013)

CEACAM expression in an in-vitro prostatitis model
por: Kube-Golovin, Irina, et al.
Publicado: (2023)

Fluorescence Molecular Targeting of Colon Cancer to Visualize the Invisible
por: Lwin, Thinzar M., et al.
Publicado: (2022)

Cytokine Secretion, Viability, and Real-Time Proliferation of Apical-Papilla Stem Cells Upon Exposure to Oral Bacteria
por: Rakhimova, Olena, et al.
Publicado: (2021)

TGFβ activates PI3K-AKT signaling via TRAF6
por: Song, Jie, et al.
Publicado: (2017)

The 2019 FASEB Science Research Conference on the TGF-β Superfamily: Signaling in Development and Disease, July 28 to August 2, 2019, West Palm Beach, Florida, USA
por: Landström, Marene, et al.
Publicado: (2019)

Near Infra-Red Photoimmunotherapy with Anti-CEA-IR700 Results in Extensive Tumor Lysis and a Significant Decrease in Tumor Burden in Orthotopic Mouse Models of Pancreatic Cancer
por: Maawy, Ali A., et al.
Publicado: (2015)

The ubiquitin-ligase TRAF6 and TGFβ type I receptor form a complex with Aurora kinase B contributing to mitotic progression and cytokinesis in cancer cells
por: Song, Jie, et al.
Publicado: (2022)

Reduced tumor growth in vivo and increased c-Abl activity in PC3 prostate cancer cells overexpressing the Shb adapter protein
por: Davoodpour, Padideh, et al.
Publicado: (2007)

The Synergistic Cooperation between TGF-β and Hypoxia in Cancer and Fibrosis
por: Mallikarjuna, Pramod, et al.
Publicado: (2022)

Tumor Growth Suppression of Pancreatic Cancer Orthotopic Xenograft Model by CEA-Targeting CAR-T Cells
por: Sato, Osamu, et al.
Publicado: (2023)

Insecticide use pattern and phenotypic susceptibility of Anopheles gambiae sensu lato to commonly used insecticides in Lower Moshi, northern Tanzania
por: Nnko, Elinas J., et al.
Publicado: (2017)

Metastatic Recurrence in a Pancreatic Cancer Patient Derived Orthotopic Xenograft (PDOX) Nude Mouse Model Is Inhibited by Neoadjuvant Chemotherapy in Combination with Fluorescence-Guided Surgery with an Anti-CA 19-9-Conjugated Fluorophore
por: Hiroshima, Yukihiko, et al.
Publicado: (2014)

Transforming growth factor-β promotes aggressiveness and invasion of clear cell renal cell carcinoma
por: Sitaram, Raviprakash T., et al.
Publicado: (2016)

VHL status regulates transforming growth factor-β signaling pathways in renal cell carcinoma
por: Mallikarjuna, Pramod, et al.
Publicado: (2018)

Complementarity of ultrasound and fluorescence imaging in an orthotopic mouse model of pancreatic cancer
por: Snyder, Cynthia S, et al.
Publicado: (2009)

Effect of Different Hosts on Feeding Patterns and Mortality of Mosquitoes (Diptera: Culicidae) and their Implications on Parasite Transmission
por: Kweka, Eliningaya J, et al.
Publicado: (2010)

TRAF6 function as a novel co-regulator of Wnt3a target genes in prostate cancer
por: Aripaka, Karthik, et al.
Publicado: (2019)

The Impact of Submicroscopic Parasitemia on Malaria Rapid Diagnosis in Northeastern Tanzania, an Area with Diverse Transmission Patterns
por: Kaaya, Robert Diotrephes, et al.
Publicado: (2022)

Fluorescence-Guided Surgery of Liver Metastasis in Orthotopic Nude-Mouse Models
por: Murakami, Takashi, et al.
Publicado: (2015)

TRAF6 promotes TGFβ-induced invasion and cell-cycle regulation via Lys63-linked polyubiquitination of Lys178 in TGFβ type I receptor
por: Sundar, Reshma, et al.
Publicado: (2015)

PKCζ facilitates lymphatic metastatic spread of prostate cancer cells in a mice xenograft model
por: Zang, Guangxiang, et al.
Publicado: (2019)

MUC1 Selectively Targets Human Pancreatic Cancer in Orthotopic Nude Mouse Models
por: Park, Jeong Youp, et al.
Publicado: (2015)

Interactions between TGF-β type I receptor and hypoxia-inducible factor-α mediates a synergistic crosstalk leading to poor prognosis for patients with clear cell renal cell carcinoma
por: Mallikarjuna, Pramod, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_v17qnehi2usb6npdhfq9vjqcec