Two Cases of Primary Ovarian Insufficiency Accompanied by High Serum Anti-Müllerian Hormone Levels and Preservation of Ovarian Follicles

Primary ovarian insufficiency (POI) is defined as the presence of amenorrhea for ≥ 4 months accompanied by evidence of two serum follicle-stimulating hormone levels in the menopausal range in women aged < 40 years. Anti-Müllerian hormone (AMH) has been recognized as the most reliable marker of ov...

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Autores principales: Chun, Sungwook, Koo, Yun Hee, Na, Yong Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Menopause 2020
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7475287/
https://www.ncbi.nlm.nih.gov/pubmed/32893516
http://dx.doi.org/10.6118/jmm.20004
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author Chun, Sungwook
Koo, Yun Hee
Na, Yong Jin
author_facet Chun, Sungwook
Koo, Yun Hee
Na, Yong Jin
author_sort Chun, Sungwook
collection PubMed
description Primary ovarian insufficiency (POI) is defined as the presence of amenorrhea for ≥ 4 months accompanied by evidence of two serum follicle-stimulating hormone levels in the menopausal range in women aged < 40 years. Anti-Müllerian hormone (AMH) has been recognized as the most reliable marker of ovarian reserve status, and its serum level is very low or undetectable in women with POI. Here we report two cases of patients who were diagnosed with POI despite high serum AMH levels and preservation of ovarian follicles, as revealed by ultrasound. In addition, we have presented a review of the current literature regarding this condition.
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spelling pubmed-74752872020-09-17 Two Cases of Primary Ovarian Insufficiency Accompanied by High Serum Anti-Müllerian Hormone Levels and Preservation of Ovarian Follicles Chun, Sungwook Koo, Yun Hee Na, Yong Jin J Menopausal Med Brief Communication Primary ovarian insufficiency (POI) is defined as the presence of amenorrhea for ≥ 4 months accompanied by evidence of two serum follicle-stimulating hormone levels in the menopausal range in women aged < 40 years. Anti-Müllerian hormone (AMH) has been recognized as the most reliable marker of ovarian reserve status, and its serum level is very low or undetectable in women with POI. Here we report two cases of patients who were diagnosed with POI despite high serum AMH levels and preservation of ovarian follicles, as revealed by ultrasound. In addition, we have presented a review of the current literature regarding this condition. The Korean Society of Menopause 2020-08 2020-06-25 /pmc/articles/PMC7475287/ /pubmed/32893516 http://dx.doi.org/10.6118/jmm.20004 Text en Copyright © 2020 by The Korean Society of Menopause http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/).
spellingShingle Brief Communication
Chun, Sungwook
Koo, Yun Hee
Na, Yong Jin
Two Cases of Primary Ovarian Insufficiency Accompanied by High Serum Anti-Müllerian Hormone Levels and Preservation of Ovarian Follicles
title Two Cases of Primary Ovarian Insufficiency Accompanied by High Serum Anti-Müllerian Hormone Levels and Preservation of Ovarian Follicles
title_full Two Cases of Primary Ovarian Insufficiency Accompanied by High Serum Anti-Müllerian Hormone Levels and Preservation of Ovarian Follicles
title_fullStr Two Cases of Primary Ovarian Insufficiency Accompanied by High Serum Anti-Müllerian Hormone Levels and Preservation of Ovarian Follicles
title_full_unstemmed Two Cases of Primary Ovarian Insufficiency Accompanied by High Serum Anti-Müllerian Hormone Levels and Preservation of Ovarian Follicles
title_short Two Cases of Primary Ovarian Insufficiency Accompanied by High Serum Anti-Müllerian Hormone Levels and Preservation of Ovarian Follicles
title_sort two cases of primary ovarian insufficiency accompanied by high serum anti-müllerian hormone levels and preservation of ovarian follicles
topic Brief Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7475287/
https://www.ncbi.nlm.nih.gov/pubmed/32893516
http://dx.doi.org/10.6118/jmm.20004
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