Pendrin stimulates a chloride absorption pathway to increase CFTR‐mediated chloride secretion from Cystic Fibrosis airway epithelia

Cystic Fibrosis (CF), an inherited multi‐system disease, is caused by mutations in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) that disrupt its ability to secrete anions from epithelia. Recovery of functional anion secretion may be curative for CF, so different components of the i...

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Detalles Bibliográficos
Autores principales: Bajko, Jeffrey, Duguid, Mei, Altmann, Steve, Hurlbut, Gregory D., Kaczmarek, J. Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7475303/
https://www.ncbi.nlm.nih.gov/pubmed/32923987
http://dx.doi.org/10.1096/fba.2020-00012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7475303/
https://www.ncbi.nlm.nih.gov/pubmed/32923987
http://dx.doi.org/10.1096/fba.2020-00012

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