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Pendrin stimulates a chloride absorption pathway to increase CFTR‐mediated chloride secretion from Cystic Fibrosis airway epithelia
Cystic Fibrosis (CF), an inherited multi‐system disease, is caused by mutations in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) that disrupt its ability to secrete anions from epithelia. Recovery of functional anion secretion may be curative for CF, so different components of the i...
Autores principales: | Bajko, Jeffrey, Duguid, Mei, Altmann, Steve, Hurlbut, Gregory D., Kaczmarek, J. Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7475303/ https://www.ncbi.nlm.nih.gov/pubmed/32923987 http://dx.doi.org/10.1096/fba.2020-00012 |
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