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Extracellular ubiquitin promotes hepatoma metastasis by mediating M2 macrophage polarization via the activation of the CXCR4/ERK signaling pathway

BACKGROUND: Stored red blood cell (RBC) transfusion has been shown to enhance the risk of cancer recurrence. However, the underlying mechanism remains unknown. At our lab, we have demonstrated that the extracellular ubiquitin (eUb) released by aged RBCs could promote tumor metastasis in a melanoma m...

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Detalles Bibliográficos
Autores principales:	Cai, Jiajing, Zhang, Qi, Qian, Xuemeng, Li, Jingdong, Qi, Qi, Sun, Ru, Han, Jia, Zhu, Xinfang, Xie, Mengyi, Guo, Xiaolan, Xia, Rong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7475394/ https://www.ncbi.nlm.nih.gov/pubmed/32953729 http://dx.doi.org/10.21037/atm-20-1054

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