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Deep vein thrombosis in a nonobstructive azoospermia male taking tamoxifen: a rare case report
Tamoxifen is used for male infertility and nonobstructive azoospermia (NOA). Although thrombosis complication of tamoxifen on the treatment of breast cancer has been reported repeatedly, there was no literature about the thrombosis complication of tamoxifen treatment on NOA. A 32-year-old man was ad...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7475655/ https://www.ncbi.nlm.nih.gov/pubmed/32944537 http://dx.doi.org/10.21037/tau-20-630 |
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author | Sun, Dalin Jin, Baofang Cai, Bin Deng, Weimin |
author_facet | Sun, Dalin Jin, Baofang Cai, Bin Deng, Weimin |
author_sort | Sun, Dalin |
collection | PubMed |
description | Tamoxifen is used for male infertility and nonobstructive azoospermia (NOA). Although thrombosis complication of tamoxifen on the treatment of breast cancer has been reported repeatedly, there was no literature about the thrombosis complication of tamoxifen treatment on NOA. A 32-year-old man was admitted to hospital for severe swelling of left lower limb, with difficulty walking. He had been diagnosed with NOA 5 months ago and had been taking tamoxifen 20 mg daily for 4 months continuously. After admission, the patient was finally diagnosed of deep vein thrombosis (DVT) with elevated D-dimer level and Doppler ultrasound of the deep venous system. After a series of effective treatments, especially the operation of percutaneous venous thromboembolism aspiration, the patient recovered rapidly and the abnormal laboratory results of coagulopathy returned to normal. Clinicians should warn about the possibility of thromboembolic complications with tamoxifen when treating male infertility. |
format | Online Article Text |
id | pubmed-7475655 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | AME Publishing Company |
record_format | MEDLINE/PubMed |
spelling | pubmed-74756552020-09-16 Deep vein thrombosis in a nonobstructive azoospermia male taking tamoxifen: a rare case report Sun, Dalin Jin, Baofang Cai, Bin Deng, Weimin Transl Androl Urol Case Report Tamoxifen is used for male infertility and nonobstructive azoospermia (NOA). Although thrombosis complication of tamoxifen on the treatment of breast cancer has been reported repeatedly, there was no literature about the thrombosis complication of tamoxifen treatment on NOA. A 32-year-old man was admitted to hospital for severe swelling of left lower limb, with difficulty walking. He had been diagnosed with NOA 5 months ago and had been taking tamoxifen 20 mg daily for 4 months continuously. After admission, the patient was finally diagnosed of deep vein thrombosis (DVT) with elevated D-dimer level and Doppler ultrasound of the deep venous system. After a series of effective treatments, especially the operation of percutaneous venous thromboembolism aspiration, the patient recovered rapidly and the abnormal laboratory results of coagulopathy returned to normal. Clinicians should warn about the possibility of thromboembolic complications with tamoxifen when treating male infertility. AME Publishing Company 2020-08 /pmc/articles/PMC7475655/ /pubmed/32944537 http://dx.doi.org/10.21037/tau-20-630 Text en 2020 Translational Andrology and Urology. All rights reserved. https://creativecommons.org/licenses/by-nc-nd/4.0/Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) . |
spellingShingle | Case Report Sun, Dalin Jin, Baofang Cai, Bin Deng, Weimin Deep vein thrombosis in a nonobstructive azoospermia male taking tamoxifen: a rare case report |
title | Deep vein thrombosis in a nonobstructive azoospermia male taking tamoxifen: a rare case report |
title_full | Deep vein thrombosis in a nonobstructive azoospermia male taking tamoxifen: a rare case report |
title_fullStr | Deep vein thrombosis in a nonobstructive azoospermia male taking tamoxifen: a rare case report |
title_full_unstemmed | Deep vein thrombosis in a nonobstructive azoospermia male taking tamoxifen: a rare case report |
title_short | Deep vein thrombosis in a nonobstructive azoospermia male taking tamoxifen: a rare case report |
title_sort | deep vein thrombosis in a nonobstructive azoospermia male taking tamoxifen: a rare case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7475655/ https://www.ncbi.nlm.nih.gov/pubmed/32944537 http://dx.doi.org/10.21037/tau-20-630 |
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