The role of lymphadenectomy at the time of radical nephroureterectomy for upper tract urothelial carcinoma

The role of lymphadenectomy (LND) at the time of radical nephroureterectomy (RNU) for upper tract urothelial carcinoma (UTUC) is controversial. The National Comprehensive Cancer Network guidelines recommend performing a template-based LND for high-risk primary tumors while the European guidelines st...

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Detalles Bibliográficos
Autores principales: Goltzman, Michael E., Gogoj, Augustyna, Ristau, Benjamin T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Review Article on Upper-Tract Urothelial Carcinoma: Current State and Future Directions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7475672/
https://www.ncbi.nlm.nih.gov/pubmed/32944550
http://dx.doi.org/10.21037/tau.2019.11.29
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author Goltzman, Michael E.
Gogoj, Augustyna
Ristau, Benjamin T.
author_facet Goltzman, Michael E.
Gogoj, Augustyna
Ristau, Benjamin T.
author_sort Goltzman, Michael E.
collection PubMed
description The role of lymphadenectomy (LND) at the time of radical nephroureterectomy (RNU) for upper tract urothelial carcinoma (UTUC) is controversial. The National Comprehensive Cancer Network guidelines recommend performing a template-based LND for high-risk primary tumors while the European guidelines state that it is not feasible to determine indication or extent of LND at the time of surgery for UTUC. Herein, we review the anatomic rationale for template-based LND, examine when a LND should be considered, and discuss the impact of LND on staging and survival outcomes.
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spelling pubmed-74756722020-09-16 The role of lymphadenectomy at the time of radical nephroureterectomy for upper tract urothelial carcinoma Goltzman, Michael E. Gogoj, Augustyna Ristau, Benjamin T. Transl Androl Urol Review Article on Upper-Tract Urothelial Carcinoma: Current State and Future Directions The role of lymphadenectomy (LND) at the time of radical nephroureterectomy (RNU) for upper tract urothelial carcinoma (UTUC) is controversial. The National Comprehensive Cancer Network guidelines recommend performing a template-based LND for high-risk primary tumors while the European guidelines state that it is not feasible to determine indication or extent of LND at the time of surgery for UTUC. Herein, we review the anatomic rationale for template-based LND, examine when a LND should be considered, and discuss the impact of LND on staging and survival outcomes. AME Publishing Company 2020-08 /pmc/articles/PMC7475672/ /pubmed/32944550 http://dx.doi.org/10.21037/tau.2019.11.29 Text en 2020 Translational Andrology and Urology. All rights reserved. https://creativecommons.org/licenses/by-nc-nd/4.0/Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) .
spellingShingle Review Article on Upper-Tract Urothelial Carcinoma: Current State and Future Directions
Goltzman, Michael E.
Gogoj, Augustyna
Ristau, Benjamin T.
The role of lymphadenectomy at the time of radical nephroureterectomy for upper tract urothelial carcinoma
title The role of lymphadenectomy at the time of radical nephroureterectomy for upper tract urothelial carcinoma
title_full The role of lymphadenectomy at the time of radical nephroureterectomy for upper tract urothelial carcinoma
title_fullStr The role of lymphadenectomy at the time of radical nephroureterectomy for upper tract urothelial carcinoma
title_full_unstemmed The role of lymphadenectomy at the time of radical nephroureterectomy for upper tract urothelial carcinoma
title_short The role of lymphadenectomy at the time of radical nephroureterectomy for upper tract urothelial carcinoma
title_sort role of lymphadenectomy at the time of radical nephroureterectomy for upper tract urothelial carcinoma
topic Review Article on Upper-Tract Urothelial Carcinoma: Current State and Future Directions
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7475672/
https://www.ncbi.nlm.nih.gov/pubmed/32944550
http://dx.doi.org/10.21037/tau.2019.11.29
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