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Advanced Sandwich Composite Cores for Patient Support in Advanced Clinical Imaging and Oncology Treatment

Ongoing advances in both imaging and treatment for oncology purposes have seen a significant rise in the use of not only the individual imaging modalities, but also their combination in single systems such as Positron Emission Tomography combined with Computed Tomography (PET–CT) and PET–MRI (Magnet...

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Autores principales: H. Morris, Robert, R. Geraldi, Nicasio, C. Pike, Lucy, Pawelke, Jörg, L. Hoffmann, Aswin, Doy, Nicola, L. Stafford, Johanna, Spicer, Abi, I. Newton, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7475909/
https://www.ncbi.nlm.nih.gov/pubmed/32806610
http://dx.doi.org/10.3390/ma13163549
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author H. Morris, Robert
R. Geraldi, Nicasio
C. Pike, Lucy
Pawelke, Jörg
L. Hoffmann, Aswin
Doy, Nicola
L. Stafford, Johanna
Spicer, Abi
I. Newton, Michael
author_facet H. Morris, Robert
R. Geraldi, Nicasio
C. Pike, Lucy
Pawelke, Jörg
L. Hoffmann, Aswin
Doy, Nicola
L. Stafford, Johanna
Spicer, Abi
I. Newton, Michael
author_sort H. Morris, Robert
collection PubMed
description Ongoing advances in both imaging and treatment for oncology purposes have seen a significant rise in the use of not only the individual imaging modalities, but also their combination in single systems such as Positron Emission Tomography combined with Computed Tomography (PET–CT) and PET–MRI (Magnetic Resonance Imaging) when planning for advanced oncology treatment, the most demanding of which is proton therapy. This has identified issues in the availability of suitable materials upon which to support the patient undergoing imaging and treatment owing to the differing requirements for each of the techniques. Sandwich composites are often selected to solve this issue but there is little information regarding optimum materials for their cores. In this paper, we presented a range of materials which are suitable for such purposes and evaluated the performance for use in terms of PET signal attenuation, proton beam stopping, MRI signal shading and X-Ray CT visibility. We found that Extruded Polystyrene offers the best compromise for patient support and positioning structures across all modalities tested, allowing for significant savings in treatment planning time and delivering more efficient treatment with lower margins.
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spelling pubmed-74759092020-09-17 Advanced Sandwich Composite Cores for Patient Support in Advanced Clinical Imaging and Oncology Treatment H. Morris, Robert R. Geraldi, Nicasio C. Pike, Lucy Pawelke, Jörg L. Hoffmann, Aswin Doy, Nicola L. Stafford, Johanna Spicer, Abi I. Newton, Michael Materials (Basel) Communication Ongoing advances in both imaging and treatment for oncology purposes have seen a significant rise in the use of not only the individual imaging modalities, but also their combination in single systems such as Positron Emission Tomography combined with Computed Tomography (PET–CT) and PET–MRI (Magnetic Resonance Imaging) when planning for advanced oncology treatment, the most demanding of which is proton therapy. This has identified issues in the availability of suitable materials upon which to support the patient undergoing imaging and treatment owing to the differing requirements for each of the techniques. Sandwich composites are often selected to solve this issue but there is little information regarding optimum materials for their cores. In this paper, we presented a range of materials which are suitable for such purposes and evaluated the performance for use in terms of PET signal attenuation, proton beam stopping, MRI signal shading and X-Ray CT visibility. We found that Extruded Polystyrene offers the best compromise for patient support and positioning structures across all modalities tested, allowing for significant savings in treatment planning time and delivering more efficient treatment with lower margins. MDPI 2020-08-12 /pmc/articles/PMC7475909/ /pubmed/32806610 http://dx.doi.org/10.3390/ma13163549 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
H. Morris, Robert
R. Geraldi, Nicasio
C. Pike, Lucy
Pawelke, Jörg
L. Hoffmann, Aswin
Doy, Nicola
L. Stafford, Johanna
Spicer, Abi
I. Newton, Michael
Advanced Sandwich Composite Cores for Patient Support in Advanced Clinical Imaging and Oncology Treatment
title Advanced Sandwich Composite Cores for Patient Support in Advanced Clinical Imaging and Oncology Treatment
title_full Advanced Sandwich Composite Cores for Patient Support in Advanced Clinical Imaging and Oncology Treatment
title_fullStr Advanced Sandwich Composite Cores for Patient Support in Advanced Clinical Imaging and Oncology Treatment
title_full_unstemmed Advanced Sandwich Composite Cores for Patient Support in Advanced Clinical Imaging and Oncology Treatment
title_short Advanced Sandwich Composite Cores for Patient Support in Advanced Clinical Imaging and Oncology Treatment
title_sort advanced sandwich composite cores for patient support in advanced clinical imaging and oncology treatment
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7475909/
https://www.ncbi.nlm.nih.gov/pubmed/32806610
http://dx.doi.org/10.3390/ma13163549
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