Cargando…

Ex Vivo Equine Cartilage Explant Osteoarthritis Model: A Metabolomics and Proteomics Study

[Image: see text] Osteoarthritis is an age-related degenerative musculoskeletal disease characterized by loss of articular cartilage, synovitis, and subchondral bone sclerosis. Osteoarthritis pathogenesis is yet to be fully elucidated with no osteoarthritis-specific biomarkers in clinical use. Ex vi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Anderson, James R., Phelan, Marie M., Foddy, Laura, Clegg, Peter D., Peffers, Mandy J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2020
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476031/ https://www.ncbi.nlm.nih.gov/pubmed/32701294 http://dx.doi.org/10.1021/acs.jproteome.0c00143

Ejemplares similares

Characterization of neopeptides in equine articular cartilage degradation
por: Peffers, Mandy Jayne, et al.
Publicado: (2015)

Optimization of Synovial Fluid Collection and Processing for NMR Metabolomics and LC-MS/MS Proteomics
por: Anderson, James R., et al.
Publicado: (2020)

MicroRNA Signatures in Cartilage Ageing and Osteoarthritis
por: Balaskas, Panagiotis, et al.
Publicado: (2023)

Effect of sugar metabolite methylglyoxal on equine lamellar explants: An ex vivo model of laminitis
por: Vercelli, Cristina, et al.
Publicado: (2021)

Transcriptomic signatures in cartilage ageing
por: Peffers, Mandy Jayne, et al.
Publicado: (2013)

Transcriptomic profiling of cartilage ageing
por: Peffers, Mandy Jayne, et al.
Publicado: (2014)

Comparison of the Effects of Interleukin-1 on Equine Articular Cartilage Explants and Cocultures of Osteochondral and Synovial Explants
por: Byron, Christopher R., et al.
Publicado: (2017)

Establishment of an Ex Vivo Inflammatory Osteoarthritis Model With Human Osteochondral Explants
por: Li, Kaihu, et al.
Publicado: (2021)

(1)H NMR Metabolomics Identifies Underlying Inflammatory Pathology in Osteoarthritis and Rheumatoid Arthritis Synovial Joints
por: Anderson, James R., et al.
Publicado: (2018)

Characterization of the Proteins Secreted by Equine Muscle-Derived Mesenchymal Stem Cells Exposed to Cartilage Explants in Osteoarthritis Model
por: Dechêne, Lola, et al.
Publicado: (2022)

Equine synovial fluid small non-coding RNA signatures in early osteoarthritis
por: Castanheira, Catarina, et al.
Publicado: (2021)

Sprifermin (rhFGF18) modulates extracellular matrix turnover in cartilage explants ex vivo
por: Reker, Ditte, et al.
Publicado: (2017)

Small non-coding RNA landscape of extracellular vesicles from a post-traumatic model of equine osteoarthritis
por: Anderson, James R., et al.
Publicado: (2022)

Comparative effect of platelet- and mesenchymal stromal cell-derived extracellular vesicles on human cartilage explants using an ex vivo inflammatory osteoarthritis model
por: Forteza-Genestra, Maria A., et al.
Publicado: (2023)

Human Osteochondral Explants as an Ex Vivo Model of Osteoarthritis for the Assessment of a Novel Class of Orthobiologics
por: Giannasi, Chiara, et al.
Publicado: (2022)

Investigation of MicroRNA Biomarkers in Equine Distal Interphalangeal Joint Osteoarthritis
por: Baker, Melissa E., et al.
Publicado: (2022)

Donor age affects proteome composition of tenocyte-derived engineered tendon
por: Turlo, Agnieszka J., et al.
Publicado: (2018)

Synovial Fluid Metabolites Differentiate between Septic and Nonseptic Joint Pathologies
por: Anderson, James R., et al.
Publicado: (2018)

Effects of Platelet-Rich Plasma Composition on Anabolic and Catabolic Activities in Equine Cartilage and Meniscal Explants
por: Kisiday, John D., et al.
Publicado: (2012)

MicroRNA Profiling in Cartilage Ageing
por: Balaskas, Panagiotis, et al.
Publicado: (2017)

SnoRNA signatures in cartilage ageing and osteoarthritis
por: Peffers, Mandy J., et al.
Publicado: (2020)

Nuclear magnetic resonance spectroscopy of biofluids for osteoarthritis
por: Clarke, Emily J, et al.
Publicado: (2020)

The synovial fluid proteome differentiates between septic and nonseptic articular pathologies
por: Anderson, James R., et al.
Publicado: (2019)

Systems approaches in osteoarthritis: Identifying routes to novel diagnostic and therapeutic strategies
por: Mueller, Alan J., et al.
Publicado: (2017)

Andrographolide Exerts Chondroprotective Activity in Equine Cartilage Explant and Suppresses Interleukin-1β-Induced MMP-2 Expression in Equine Chondrocyte Culture
por: Tangyuenyong, Siriwan, et al.
Publicado: (2014)

Explanting Is an Ex Vivo Model of Renal Epithelial-Mesenchymal Transition
por: Winbanks, Catherine E., et al.
Publicado: (2011)

Models of ex vivo explant cultures: applications in bone research
por: Marino, Silvia, et al.
Publicado: (2016)

High throughput proteomic analysis of the secretome in an explant model of articular cartilage inflammation
por: Clutterbuck, Abigail L., et al.
Publicado: (2011)

Bevacizumab suppressed degenerative changes in articular cartilage explants from patients with osteoarthritis of the knee
por: Sotozawa, Masaichi, et al.
Publicado: (2023)

Ex vivo physiological compression of human osteoarthritis cartilage modulates cellular and matrix components
por: Dolzani, Paolo, et al.
Publicado: (2019)

Identification of Equid herpesvirus 2 in tissue-engineered equine tendon
por: Wardle, Roisin, et al.
Publicado: (2017)

Matrix assisted laser desorption ionization mass spectrometry imaging identifies markers of ageing and osteoarthritic cartilage
por: Peffers, Mandy J, et al.
Publicado: (2014)

Tenascins Interfere With Remyelination in an Ex Vivo Cerebellar Explant Model of Demyelination
por: Bauch, Juliane, et al.
Publicado: (2022)

Phospholipid dynamics in ex vivo lung cancer and normal lung explants
por: Lesko, Julia, et al.
Publicado: (2021)

Novel Ex Vivo Human Osteochondral Explant Model of Knee and Spine Osteoarthritis Enables Assessment of Inflammatory and Drug Treatment Responses
por: Geurts, Jeroen, et al.
Publicado: (2018)

Proteomic Analysis of the Meniscus Cartilage in Osteoarthritis
por: Park, Jisook, et al.
Publicado: (2021)

Characterisation of Gel-Forming Mucins Produced In Vivo and In Ex Vivo Conjunctival Explant Cultures
por: Van Acker, Sara I., et al.
Publicado: (2021)

Pixelated Microfluidics for Drug Screening on Tumour Spheroids and Ex Vivo Microdissected Tumour Explants
por: Dorrigiv, Dina, et al.
Publicado: (2023)

Multi-Omic Temporal Landscape of Plasma and Synovial Fluid-Derived Extracellular Vesicles Using an Experimental Model of Equine Osteoarthritis
por: Anderson, James R., et al.
Publicado: (2023)

A proteomic analysis of chondrogenic, osteogenic and tenogenic constructs from ageing mesenchymal stem cells
por: Peffers, Mandy J., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_8a01irj8rn7q7qt9dvq8v7c460