SHP2 promotes proliferation of breast cancer cells through regulating Cyclin D1 stability via the PI3K/AKT/GSK3β signaling pathway

Objective: The tyrosine phosphatase SHP2 has a dual role in cancer initiation and progression in a tissue type-dependent manner. Several studies have linked SHP2 to the aggressive behavior of breast cancer cells and poorer outcomes in people with cancer. Nevertheless, the mechanistic details of how...

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Detalles Bibliográficos
Autores principales: Yuan, Yue, Fan, Yanling, Gao, Zicong, Sun, Xuan, Zhang, He, Wang, Zhiyong, Cui, Yanfen, Song, Weijie, Wang, Zhaosong, Zhang, Fei, Niu, Ruifang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Compuscript 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476086/
https://www.ncbi.nlm.nih.gov/pubmed/32944401
http://dx.doi.org/10.20892/j.issn.2095-3941.2020.0056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476086/
https://www.ncbi.nlm.nih.gov/pubmed/32944401
http://dx.doi.org/10.20892/j.issn.2095-3941.2020.0056

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