Targeting fatty acid synthase sensitizes human nasopharyngeal carcinoma cells to radiation via downregulating frizzled class receptor 10

Objective: Our aim was to test the hypothesis that fatty acid synthase (FASN) expression contributes to radioresistance of nasopharyngeal carcinoma (NPC) cells and that inhibiting FASN enhances radiosensitivity. Methods: Targeting FASN using epigallocatechin gallate (EGCG) or RNA interference in NPC...

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Detalles Bibliográficos
Autores principales: Chen, Jiongyu, Zhang, Fan, Ren, Xiaosha, Wang, Yahui, Huang, Wenhe, Zhang, Jianting, Cui, Yukun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Compuscript 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476091/
https://www.ncbi.nlm.nih.gov/pubmed/32944403
http://dx.doi.org/10.20892/j.issn.2095-3941.2020.0219

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