Kinetochore protein MAD1 participates in the DNA damage response through ataxia-telangiectasia mutated kinase-mediated phosphorylation and enhanced interaction with KU80

Objective: Mitotic arrest-deficient protein 1 (MAD1) is a kinetochore protein essential for the mitotic spindle checkpoint. Proteomic studies have indicated that MAD1 is a component of the DNA damage response (DDR) pathway. However, whether and how MAD1 might be directly involved in the DDR is large...

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Detalles Bibliográficos
Autores principales: Xiao, Mingming, Li, Xuesong, Su, Yang, Liu, Zhuang, Han, Yamei, Wang, Shuai, Zeng, Qinghua, Liu, Hong, Hao, Jianwei, Xu, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Compuscript 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476095/
https://www.ncbi.nlm.nih.gov/pubmed/32944396
http://dx.doi.org/10.20892/j.issn.2095-3941.2020.0044

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