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An isoflavone derivative potently inhibits the angiogenesis and progression of triple-negative breast cancer by targeting the MTA2/SerRS/VEGFA pathway

Objective: Angiogenesis plays a vital role in tumor growth and metastasis. Here, we aimed to find novel efficient antiangiogenic molecules targeting vascular endothelial growth factor A (VEGFA ) at the transcriptional level to treat triple-negative breast cancer (TNBC). Methods: We used a cell-based...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaotong, Zou, Gengyi, Li, Xiyang, Wang, Lun, Xie, Tianyu, Zhao, Jin, Wang, Longlong, Jiao, Shunchang, Xiang, Rong, Ye, Haoyu, Shi, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Compuscript 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476100/
https://www.ncbi.nlm.nih.gov/pubmed/32944400
http://dx.doi.org/10.20892/j.issn.2095-3941.2020.0010