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Tumor necrosis factor alpha receptor 1 deficiency in hepatocytes does not protect from non-alcoholic steatohepatitis, but attenuates insulin resistance in mice

BACKGROUND: End-stage liver disease caused by non-alcoholic steatohepatitis (NASH) is the second leading indication for liver transplantation. To date, only moderately effective pharmacotherapies exist to treat NASH. Understanding the pathogenesis of NASH is therefore crucial for the development of...

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Detalles Bibliográficos
Autores principales:	Bluemel, Sena, Wang, Yanhan, Lee, Suhan, Schnabl, Bernd
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Baishideng Publishing Group Inc 2020
Materias:	Basic Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476178/ https://www.ncbi.nlm.nih.gov/pubmed/32952340 http://dx.doi.org/10.3748/wjg.v26.i33.4933

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