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ADAMTS18 Deficiency Leads to Pulmonary Hypoplasia and Bronchial Microfibril Accumulation
ADAMTSs (a disintegrin and metalloproteinase with thrombospondin motifs) are secreted metalloproteinases that play a major role in the assembly and degradation of the extracellular matrix (ECM). In this study, we show that ADAMTS18, produced by the epithelial cells of distal airways and mesenchymal...
Autores principales: | Lu, Tiantian, Lin, Xiaotian, Pan, Yi-Hsuan, Yang, Ning, Ye, Shuai, Zhang, Qi, Wang, Caiyun, Zhu, Rui, Zhang, Tianhao, Wisniewski, Thomas M., Cao, Zhongwei, Ding, Bi-Sen, Dang, Suying, Zhang, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476315/ https://www.ncbi.nlm.nih.gov/pubmed/32882513 http://dx.doi.org/10.1016/j.isci.2020.101472 |
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