Cargando…

Dual UTR-A novel 5′ untranslated region design for synthetic biology applications

Bacterial 5′ untranslated regions of mRNA (UTR) involve in a complex regulation of gene expression; however, the exact sequence features contributing to gene regulation are not yet fully understood. In this study, we report the design of a novel 5′ UTR, dual UTR, utilizing the transcriptional and tr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Balzer Le, Simone, Onsager, Ingerid, Lorentzen, Jon Andreas, Lale, Rahmi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476403/ https://www.ncbi.nlm.nih.gov/pubmed/32995550 http://dx.doi.org/10.1093/synbio/ysaa006

Ejemplares similares

Importance of the 5′ regulatory region to bacterial synthetic biology applications
por: Tietze, Lisa, et al.
Publicado: (2021)

Identification and Cross-Characterisation of Artificial Promoters and 5′ Untranslated Regions in Vibrio natriegens
por: Tietze, Lisa, et al.
Publicado: (2022)

Identification and Characterization of 5′ Untranslated Regions (5′UTRs) in Zymomonas mobilis as Regulatory Biological Parts
por: Cho, Seung Hee, et al.
Publicado: (2017)

DEFB1 gene 5′ untranslated region (UTR) polymorphisms in inflammatory bowel diseases
por: Zanin, Valentina, et al.
Publicado: (2012)

The expression of recombinant genes in Escherichia coli can be strongly stimulated at the transcript production level by mutating the DNA‐region corresponding to the 5′‐untranslated part of mRNA
por: Berg, Laila, et al.
Publicado: (2009)

Improving plant transient expression through the rational design of synthetic 5′ and 3′ untranslated regions
por: Peyret, Hadrien, et al.
Publicado: (2019)

Statistical analysis supports UTR (untranslated region) deletion theory in SARS-CoV-2
por: Xu, Zhaobin, et al.
Publicado: (2022)

3'-UTR SIRF: A database for identifying clusters of whort interspersed repeats in 3' untranslated regions
por: Andken, Benjamin B, et al.
Publicado: (2007)

Structural diversity and biological role of the 5’ untranslated regions of picornavirus
por: Peng, Tingyu, et al.
Publicado: (2023)

Functional characterization of 5′ untranslated region (UTR) secondary RNA structures in the replication of tick-borne encephalitis virus in mammalian cells
por: Upstone, Laura, et al.
Publicado: (2023)

The genomic region of the 3′ untranslated region (3′UTR) of PHO84, rather than the antisense RNA, promotes gene repression
por: Hegazy, Youssef A, et al.
Publicado: (2023)

Comparative analysis of hepatitis C virus phylogenies from coding and non-coding regions: the 5' untranslated region (UTR) fails to classify subtypes
por: Hraber, Peter T, et al.
Publicado: (2006)

A 3′-Untranslated Region (3′UTR) Induces Organ Adhesion by Regulating miR-199a* Functions
por: Lee, Daniel Y., et al.
Publicado: (2009)

Association of Dengue Virus Serotypes 1&2 with Severe Dengue Having Deletions in Their 3′Untranslated Regions (3′UTRs)
por: Maisnam, Deepti, et al.
Publicado: (2023)

The 5′-Untranslated Region of Picornaviral Genomes
por: Agol, Vadim I.
Publicado: (1991)

Scan for Motifs: a webserver for the analysis of post-transcriptional regulatory elements in the 3′ untranslated regions (3′ UTRs) of mRNAs
por: Biswas, Ambarish, et al.
Publicado: (2014)

Characterization of single nucleotide polymorphism in the 5'-untranslated region (5'-UTR) of Lactoferrin gene and its association with reproductive parameters and uterine infection in dairy cattle
por: Hajibemani, Abolfazl, et al.
Publicado: (2012)

The ODC 3′-Untranslated Region and 5′-Untranslated Region Contain cis-Regulatory Elements: Implications for Carcinogenesis
por: Nowotarski, Shannon L., et al.
Publicado: (2017)

Detection of Differentially Expressed Cleavage Site Intervals Within 3′ Untranslated Regions Using CSI-UTR Reveals Regulated Interaction Motifs
por: Harrison, Benjamin J., et al.
Publicado: (2019)

Systematic Evaluation of HLA-G 3’Untranslated Region Variants in Locally Advanced, Non-Metastatic Breast Cancer Patients: UTR-1, 2 or UTR-4 are Predictors for Therapy and Disease Outcome
por: Rebmann, Vera, et al.
Publicado: (2022)

The 5′ and 3′ Untranslated Regions of the Flaviviral Genome
por: Ng, Wy Ching, et al.
Publicado: (2017)

Untranslated regions of mRNAs
por: Mignone, Flavio, et al.
Publicado: (2002)

A universal approach to gene expression engineering
por: Lale, Rahmi, et al.
Publicado: (2022)

A Novel Distinct Genetic Variant of Tomato Torrado Virus with Substantially Shorter RNA1-Specific 3’Untranslated Region (3’UTR)
por: Budziszewska, Marta, et al.
Publicado: (2021)

Structure of the 5′ Untranslated Region of Enteroviral Genomic RNA
por: Mahmud, Bejan, et al.
Publicado: (2019)

Polymorphic variability in the 3' untranslated region (UTR) of IL12B is associated with susceptibility to severe anaemia in Kenyan children with acute Plasmodium falciparum malaria
por: Ong'echa, John M, et al.
Publicado: (2011)

A comparative analysis of the properties of regulated promoter systems commonly used for recombinant gene expression in Escherichia coli
por: Balzer, Simone, et al.
Publicado: (2013)

Properties of untranslated regions of the S. cerevisiae genome
por: Tuller, Tamir, et al.
Publicado: (2009)

Conserved tertiary structure elements in the 5′ untranslated region of human enteroviruses and rhinoviruses
por: Le, Shu-Yun, et al.
Publicado: (1992)

Annotating high-impact 5′untranslated region variants with the UTRannotator
por: Zhang, Xiaolei, et al.
Publicado: (2020)

The Roles of the 5′ and 3′ Untranslated Regions in Human Astrovirus Replication
por: Wildi, Nicole, et al.
Publicado: (2023)

Pathway optimization by re-design of untranslated regions for L-tyrosine production in Escherichia coli
por: Cheol Kim, Seong, et al.
Publicado: (2015)

The biological basis for microRNA target restriction to the 3' untranslated region in mammalian mRNAs
por: Gu, Shuo, et al.
Publicado: (2009)

siRNA Design to Silence the 3′UTR Region of Zika Virus
por: Perez-Mendez, María, et al.
Publicado: (2020)

Genome-wide functional analysis of human 5' untranslated region introns
por: Cenik, Can, et al.
Publicado: (2010)

Regulation of estrogen receptor beta by 5' untranslated regions in breast carcinogenesis
por: Smith, L, et al.
Publicado: (2008)

The genomic features that affect the lengths of 5’ untranslated regions in multicellular eukaryotes
por: Chen, Chun-Hsi, et al.
Publicado: (2011)

Constitutive translation of human α-synuclein is mediated by the 5′-untranslated region
por: Koukouraki, Pelagia, et al.
Publicado: (2016)

Functional and structural basis of extreme conservation in vertebrate 5’ untranslated regions
por: Byeon, Gun Woo, et al.
Publicado: (2021)

Conserved Sequences in the 5′ and 3′ Untranslated Regions of Jingmenvirus Group Representatives
por: Litov, Alexander G., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_v015b92sbh7qalot2n9ukrqkia