Cargando…
Successful BRAF/MEK inhibition in a patient with BRAF(V600E)-mutated extrapancreatic acinar cell carcinoma
Pancreatic acinar cell carcinoma (PAC) is a rare disease with a poor prognosis. Treatment options for metastatic PAC are limited and often follow chemotherapeutic regimens for pancreatic ductal adenocarcinoma. Although recurrent genomic alterations, such as BRAF fusions and defects in genes involved...
Autores principales: | Busch, Elena, Kreutzfeldt, Simon, Agaimy, Abbas, Mechtersheimer, Gunhild, Horak, Peter, Brors, Benedikt, Hutter, Barbara, Fröhlich, Martina, Uhrig, Sebastian, Mayer, Philipp, Schröck, Evelin, Stenzinger, Albrecht, Glimm, Hanno, Jäger, Dirk, Springfeld, Christoph, Fröhling, Stefan, Zschäbitz, Stefanie |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476408/ https://www.ncbi.nlm.nih.gov/pubmed/32843432 http://dx.doi.org/10.1101/mcs.a005553 |
Ejemplares similares
-
Tissue-Agnostic Activity of BRAF plus MEK Inhibitor in BRAF V600–Mutant Tumors
por: Adashek, Jacob J., et al.
Publicado: (2022) -
MEK inhibitors in non-V600 BRAF mutations and fusions
por: Johnson, Douglas B., et al.
Publicado: (2020) -
BRAF, MEK and EGFR inhibition as treatment strategies in BRAF V600E metastatic colorectal cancer
por: Ros, Javier, et al.
Publicado: (2021) -
Histological transformation to gliosarcoma with combined BRAF/MEK inhibition in BRAF V600E mutated glioblastoma
por: Nelson, Blessie Elizabeth, et al.
Publicado: (2023) -
BRAF and MEK Inhibitor Treatment for Metastatic Undifferentiated Sarcoma of the Spermatic Cord with BRAF V600E Mutation
por: Saijo, Ken, et al.
Publicado: (2022)