Failure of tofacitinib to achieve an objective response in a DDX3X-MLLT10 T-lymphoblastic leukemia with activating JAK3 mutations

T-cell lymphoblastic lymphoma/T-cell acute lymphoblastic leukemia (T-LBL/T ALL) is an aggressive hematological malignancy arising from malignant transformation of T-cell progenitors with poor prognosis in adult patients. Outcomes are particularly dismal in the relapsed/refractory setting, and therap...

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Detalles Bibliográficos
Autores principales: Wong, Jonathan, Wall, Meaghan, Corboy, Gregory Philip, Taubenheim, Nadine, Gregory, Gareth Peter, Opat, Stephen, Shortt, Jake
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476415/
https://www.ncbi.nlm.nih.gov/pubmed/32843425
http://dx.doi.org/10.1101/mcs.a004994

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