Efficient [(NHC)Au(NTf(2))]-catalyzed hydrohydrazidation of terminal and internal alkynes

The efficient hydrohydrazidation of terminal (6a–r, 18 examples, 0.1–0.2 mol % [(NHC)Au(NTf(2))], T = 60 °C) and internal alkynes (7a–j, 10 examples, 0.2–0.5 mol % [(NHC)Au(NTf(2))], T = 60–80 °C) utilizing a complex with a sterically demanding bispentiptycenyl-substituted NHC ligand and the benign...

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Detalles Bibliográficos
Autores principales: Heidrich, Maximillian, Plenio, Herbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2020
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476583/
https://www.ncbi.nlm.nih.gov/pubmed/32952724
http://dx.doi.org/10.3762/bjoc.16.175
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author Heidrich, Maximillian
Plenio, Herbert
author_facet Heidrich, Maximillian
Plenio, Herbert
author_sort Heidrich, Maximillian
collection PubMed
description The efficient hydrohydrazidation of terminal (6a–r, 18 examples, 0.1–0.2 mol % [(NHC)Au(NTf(2))], T = 60 °C) and internal alkynes (7a–j, 10 examples, 0.2–0.5 mol % [(NHC)Au(NTf(2))], T = 60–80 °C) utilizing a complex with a sterically demanding bispentiptycenyl-substituted NHC ligand and the benign reaction solvent anisole, is reported.
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spelling pubmed-74765832020-09-18 Efficient [(NHC)Au(NTf(2))]-catalyzed hydrohydrazidation of terminal and internal alkynes Heidrich, Maximillian Plenio, Herbert Beilstein J Org Chem Full Research Paper The efficient hydrohydrazidation of terminal (6a–r, 18 examples, 0.1–0.2 mol % [(NHC)Au(NTf(2))], T = 60 °C) and internal alkynes (7a–j, 10 examples, 0.2–0.5 mol % [(NHC)Au(NTf(2))], T = 60–80 °C) utilizing a complex with a sterically demanding bispentiptycenyl-substituted NHC ligand and the benign reaction solvent anisole, is reported. Beilstein-Institut 2020-08-26 /pmc/articles/PMC7476583/ /pubmed/32952724 http://dx.doi.org/10.3762/bjoc.16.175 Text en Copyright © 2020, Heidrich and Plenio https://creativecommons.org/licenses/by/4.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0). Please note that the reuse, redistribution and reproduction in particular requires that the authors and source are credited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Full Research Paper
Heidrich, Maximillian
Plenio, Herbert
Efficient [(NHC)Au(NTf(2))]-catalyzed hydrohydrazidation of terminal and internal alkynes
title Efficient [(NHC)Au(NTf(2))]-catalyzed hydrohydrazidation of terminal and internal alkynes
title_full Efficient [(NHC)Au(NTf(2))]-catalyzed hydrohydrazidation of terminal and internal alkynes
title_fullStr Efficient [(NHC)Au(NTf(2))]-catalyzed hydrohydrazidation of terminal and internal alkynes
title_full_unstemmed Efficient [(NHC)Au(NTf(2))]-catalyzed hydrohydrazidation of terminal and internal alkynes
title_short Efficient [(NHC)Au(NTf(2))]-catalyzed hydrohydrazidation of terminal and internal alkynes
title_sort efficient [(nhc)au(ntf(2))]-catalyzed hydrohydrazidation of terminal and internal alkynes
topic Full Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476583/
https://www.ncbi.nlm.nih.gov/pubmed/32952724
http://dx.doi.org/10.3762/bjoc.16.175
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AT plenioherbert efficientnhcauntf2catalyzedhydrohydrazidationofterminalandinternalalkynes

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