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Access to highly substituted oxazoles by the reaction of α-azidochalcone with potassium thiocyanate
The reactivity of α-azidochalcones has been explored for the preparation of highly substituted oxazoles via a 2H-azirine intermediate. The azidochalcones, when treated with potassium thiocyanate in the presence of potassium persulfate, lead to 2,4,5-trisubstituted oxazoles in good yields. Incidental...
Autores principales: | Harisha, Mysore Bhyrappa, Dhanalakshmi, Pandi, Suresh, Rajendran, Kumar, Raju Ranjith, Muthusubramanian, Shanmugam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Beilstein-Institut
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476590/ https://www.ncbi.nlm.nih.gov/pubmed/32952727 http://dx.doi.org/10.3762/bjoc.16.178 |
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