Viral load of SARS-CoV-2 across patients and compared to other respiratory viruses

RT-PCRs to detect SARS-CoV-2 RNA is key to manage the COVID-19 pandemic. We analyzed SARS-CoV-2 viral loads from 22′323 RT-PCR results according to samples types, gender, age, and health units. Viral load did not show any difference across age and appears to be a poor predictor of disease outcome. S...

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Autores principales: Jacot, Damien, Greub, Gilbert, Jaton, Katia, Opota, Onya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Masson SAS on behalf of Institut Pasteur. 2020
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476607/
https://www.ncbi.nlm.nih.gov/pubmed/32911086
http://dx.doi.org/10.1016/j.micinf.2020.08.004
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author Jacot, Damien
Greub, Gilbert
Jaton, Katia
Opota, Onya
author_facet Jacot, Damien
Greub, Gilbert
Jaton, Katia
Opota, Onya
author_sort Jacot, Damien
collection PubMed
description RT-PCRs to detect SARS-CoV-2 RNA is key to manage the COVID-19 pandemic. We analyzed SARS-CoV-2 viral loads from 22′323 RT-PCR results according to samples types, gender, age, and health units. Viral load did not show any difference across age and appears to be a poor predictor of disease outcome. SARS-CoV-2 viral load showed similar high viral loads than the one observed for RSV and influenza B. The importance of viral load to predict contagiousness and to assess disease progression is discussed.
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spelling pubmed-74766072020-09-08 Viral load of SARS-CoV-2 across patients and compared to other respiratory viruses Jacot, Damien Greub, Gilbert Jaton, Katia Opota, Onya Microbes Infect Short Communication RT-PCRs to detect SARS-CoV-2 RNA is key to manage the COVID-19 pandemic. We analyzed SARS-CoV-2 viral loads from 22′323 RT-PCR results according to samples types, gender, age, and health units. Viral load did not show any difference across age and appears to be a poor predictor of disease outcome. SARS-CoV-2 viral load showed similar high viral loads than the one observed for RSV and influenza B. The importance of viral load to predict contagiousness and to assess disease progression is discussed. Published by Elsevier Masson SAS on behalf of Institut Pasteur. 2020 2020-09-07 /pmc/articles/PMC7476607/ /pubmed/32911086 http://dx.doi.org/10.1016/j.micinf.2020.08.004 Text en © 2020 Published by Elsevier Masson SAS on behalf of Institut Pasteur. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Short Communication
Jacot, Damien
Greub, Gilbert
Jaton, Katia
Opota, Onya
Viral load of SARS-CoV-2 across patients and compared to other respiratory viruses
title Viral load of SARS-CoV-2 across patients and compared to other respiratory viruses
title_full Viral load of SARS-CoV-2 across patients and compared to other respiratory viruses
title_fullStr Viral load of SARS-CoV-2 across patients and compared to other respiratory viruses
title_full_unstemmed Viral load of SARS-CoV-2 across patients and compared to other respiratory viruses
title_short Viral load of SARS-CoV-2 across patients and compared to other respiratory viruses
title_sort viral load of sars-cov-2 across patients and compared to other respiratory viruses
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476607/
https://www.ncbi.nlm.nih.gov/pubmed/32911086
http://dx.doi.org/10.1016/j.micinf.2020.08.004
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