Cargando…
Treatment of Perianal Fistulas in Crohn’s Disease, Seton Versus Anti-TNF Versus Surgical Closure Following Anti-TNF [PISA]: A Randomised Controlled Trial
BACKGROUND AND AIMS: Most patients with perianal Crohn’s fistula receive medical treatment with anti-tumour necrosis factor [TNF], but the results of anti-TNF treatment have not been directly compared with chronic seton drainage or surgical closure. The aim of this study was to assess if chronic set...
Autores principales: | Wasmann, Karin A, de Groof, E Joline, Stellingwerf, Merel E, D’Haens, Geert R, Ponsioen, Cyriel Y, Gecse, Krisztina B, Dijkgraaf, Marcel G W, Gerhards, Michael F, Jansen, Jeroen M, Pronk, Apollo, van Tuyl, Sebastiaan A C, Zimmerman, David D E, Bruin, Karlien F, Spinelli, Antonino, Danese, Silvio, van der Bilt, Jarmila D W, Mundt, Marco W, Bemelman, Willem A, Buskens, Christianne J |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476637/ https://www.ncbi.nlm.nih.gov/pubmed/31919501 http://dx.doi.org/10.1093/ecco-jcc/jjaa004 |
Ejemplares similares
-
Multimodal treatment of perianal fistulas in Crohn’s disease: seton versus anti-TNF versus advancement plasty (PISA): study protocol for a randomized controlled trial
por: de Groof, E. Joline, et al.
Publicado: (2015) -
Short-term anti-TNF therapy with surgical closure versus anti-TNF therapy alone for Crohn's perianal fistulas (PISA-II): long-term outcomes of an international, multicentre patient preference, randomised controlled trial
por: Meima - van Praag, Elise M., et al.
Publicado: (2023) -
Knotless seton for perianal fistulas: feasibility and effect on perianal disease activity
por: Stellingwerf, Merel E., et al.
Publicado: (2020) -
Author Correction: Knotless seton for perianal fistulas: feasibility and effect on perianal disease activity
por: Stellingwerf, Merel E., et al.
Publicado: (2021) -
Anti-TNF therapy in IBD exerts its therapeutic effect through macrophage IL-10 signalling
por: Koelink, Pim J, et al.
Publicado: (2020)