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Penetrance of Colorectal Cancer Among Mismatch Repair Gene Mutation Carriers: A Meta-Analysis

BACKGROUND: Lynch syndrome, the most common colorectal cancer (CRC) syndrome, is caused by germline mismatch repair (MMR) genes. Precise estimates of age-specific risks are crucial for sound counseling of individuals managing a genetic predisposition to cancer, but published risk estimates vary. The...

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Detalles Bibliográficos
Autores principales:	Wang, Cathy, Wang, Yan, Hughes, Kevin S, Parmigiani, Giovanni, Braun, Danielle
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Meta-Analysis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476651/ https://www.ncbi.nlm.nih.gov/pubmed/32923933 http://dx.doi.org/10.1093/jncics/pkaa027

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