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Penetrance of Colorectal Cancer Among Mismatch Repair Gene Mutation Carriers: A Meta-Analysis
BACKGROUND: Lynch syndrome, the most common colorectal cancer (CRC) syndrome, is caused by germline mismatch repair (MMR) genes. Precise estimates of age-specific risks are crucial for sound counseling of individuals managing a genetic predisposition to cancer, but published risk estimates vary. The...
Autores principales: | Wang, Cathy, Wang, Yan, Hughes, Kevin S, Parmigiani, Giovanni, Braun, Danielle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476651/ https://www.ncbi.nlm.nih.gov/pubmed/32923933 http://dx.doi.org/10.1093/jncics/pkaa027 |
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