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Denosumab Therapy for Giant-cell Tumor of the Lumbar Spine: A Case Report and Immunohistochemical Examination

INTRODUCTION: Denosumab, a monoclonal antibody that inhibits the receptor activator of nuclear factor-kappa (RANK) ligand, has been reported to reduce tumor size and progression, promote bone mineralization reconstruction, and increase bone density in patients with giant-cell tumor of bone (GCTB). H...

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Detalles Bibliográficos
Autores principales: Yayama, Takafumi, Mori, Kanji, Nakamura, Akira, Mimura, Tomohiro, Imai, Shinji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Indian Orthopaedic Research Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476695/
https://www.ncbi.nlm.nih.gov/pubmed/32953662
http://dx.doi.org/10.13107/jocr.2020.v10.i02.1706