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Denosumab Therapy for Giant-cell Tumor of the Lumbar Spine: A Case Report and Immunohistochemical Examination
INTRODUCTION: Denosumab, a monoclonal antibody that inhibits the receptor activator of nuclear factor-kappa (RANK) ligand, has been reported to reduce tumor size and progression, promote bone mineralization reconstruction, and increase bone density in patients with giant-cell tumor of bone (GCTB). H...
Autores principales: | Yayama, Takafumi, Mori, Kanji, Nakamura, Akira, Mimura, Tomohiro, Imai, Shinji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Indian Orthopaedic Research Group
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476695/ https://www.ncbi.nlm.nih.gov/pubmed/32953662 http://dx.doi.org/10.13107/jocr.2020.v10.i02.1706 |
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