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Small Cell Prostate Cancer with Atypical Presentation –A Case Report and Review of Literature

INTRODUCTION: Prostate cancer is one of the leading causes of death due to carcinoma in developed countries due to metastasis. Most of the patient at the time of diagnosis has shown metastasis. Metastasis to bone leads to various skeletal-related events such as fracture and neural compression leadin...

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Autores principales: Purohit, Shaligram, Bhaladhare, Shubhanshu, Marathe, Nandan, Shah, Swapneel, Raj, Aditya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Indian Orthopaedic Research Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476697/
https://www.ncbi.nlm.nih.gov/pubmed/32953655
http://dx.doi.org/10.13107/jocr.2020.v10.i02.1692
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author Purohit, Shaligram
Bhaladhare, Shubhanshu
Marathe, Nandan
Shah, Swapneel
Raj, Aditya
author_facet Purohit, Shaligram
Bhaladhare, Shubhanshu
Marathe, Nandan
Shah, Swapneel
Raj, Aditya
author_sort Purohit, Shaligram
collection PubMed
description INTRODUCTION: Prostate cancer is one of the leading causes of death due to carcinoma in developed countries due to metastasis. Most of the patient at the time of diagnosis has shown metastasis. Metastasis to bone leads to various skeletal-related events such as fracture and neural compression leading to increase morbidity in such patients. An early diagnosis leads to favorable outcomes. Skeletal metastasis is usually presented as osteoblastic localized lesion in the spine or pelvis. Here, we like to present a case of prostatic metastasis in a patient with widespread metastasis making the diagnosis in such condition a challenging issue. CASE REPORT: A 61-year-old male comes with a complaint of right hip pain who has been diagnosed in some other clinic as a case of osteopoikilosis after an X-ray of the pelvis with both hips. However, on the further skeletal analysis found to involve most of the skeletal system with the diffuse osteolytic lesion. A bone scan, lab investigations helped in the arrival of diagnosis of atypical prostatic metastasis. CONCLUSION: Prostate cancer is less likely to present as widespread osteolytic lesions. A very few case reports have been found in the literature regarding such presentation. This case demonstrates how to differentiate between metastasis and other common condition showing such presentation leading to an early diagnosis and thus improving the overall mortality and morbidity of the patients.
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spelling pubmed-74766972020-09-18 Small Cell Prostate Cancer with Atypical Presentation –A Case Report and Review of Literature Purohit, Shaligram Bhaladhare, Shubhanshu Marathe, Nandan Shah, Swapneel Raj, Aditya J Orthop Case Rep Case Report INTRODUCTION: Prostate cancer is one of the leading causes of death due to carcinoma in developed countries due to metastasis. Most of the patient at the time of diagnosis has shown metastasis. Metastasis to bone leads to various skeletal-related events such as fracture and neural compression leading to increase morbidity in such patients. An early diagnosis leads to favorable outcomes. Skeletal metastasis is usually presented as osteoblastic localized lesion in the spine or pelvis. Here, we like to present a case of prostatic metastasis in a patient with widespread metastasis making the diagnosis in such condition a challenging issue. CASE REPORT: A 61-year-old male comes with a complaint of right hip pain who has been diagnosed in some other clinic as a case of osteopoikilosis after an X-ray of the pelvis with both hips. However, on the further skeletal analysis found to involve most of the skeletal system with the diffuse osteolytic lesion. A bone scan, lab investigations helped in the arrival of diagnosis of atypical prostatic metastasis. CONCLUSION: Prostate cancer is less likely to present as widespread osteolytic lesions. A very few case reports have been found in the literature regarding such presentation. This case demonstrates how to differentiate between metastasis and other common condition showing such presentation leading to an early diagnosis and thus improving the overall mortality and morbidity of the patients. Indian Orthopaedic Research Group 2020 /pmc/articles/PMC7476697/ /pubmed/32953655 http://dx.doi.org/10.13107/jocr.2020.v10.i02.1692 Text en Copyright: © Indian Orthopaedic Research Group http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Purohit, Shaligram
Bhaladhare, Shubhanshu
Marathe, Nandan
Shah, Swapneel
Raj, Aditya
Small Cell Prostate Cancer with Atypical Presentation –A Case Report and Review of Literature
title Small Cell Prostate Cancer with Atypical Presentation –A Case Report and Review of Literature
title_full Small Cell Prostate Cancer with Atypical Presentation –A Case Report and Review of Literature
title_fullStr Small Cell Prostate Cancer with Atypical Presentation –A Case Report and Review of Literature
title_full_unstemmed Small Cell Prostate Cancer with Atypical Presentation –A Case Report and Review of Literature
title_short Small Cell Prostate Cancer with Atypical Presentation –A Case Report and Review of Literature
title_sort small cell prostate cancer with atypical presentation –a case report and review of literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476697/
https://www.ncbi.nlm.nih.gov/pubmed/32953655
http://dx.doi.org/10.13107/jocr.2020.v10.i02.1692
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