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A Rare Presentation of Spinal Schwannoma Causing Conus Medullaris Syndrome: A Case Series on Surgical Outcome.

INTRODUCTION: Spinal schwannoma can occur anywhere along the spinal cord but is predominantly seen in the cervical and thoracic region.It composes mainly of well-differentiated schwann cell and is benign in nature. It is typically seen in the peripheral nerves and is commonly associated with neurofi...

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Autores principales: Khan, Ed Simor Khan Bin MorJapar, Thean, Charles Ang Poh, Zakaria, Zamzuri Bin, Awang, Mohamed Saufi Bin, Karupiah, Rajandra Kumar, Awang, MohdShukrimi Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Indian Orthopaedic Research Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476700/
https://www.ncbi.nlm.nih.gov/pubmed/32953668
http://dx.doi.org/10.13107/jocr.2020.v10.i02.1718
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author Khan, Ed Simor Khan Bin MorJapar
Thean, Charles Ang Poh
Zakaria, Zamzuri Bin
Awang, Mohamed Saufi Bin
Karupiah, Rajandra Kumar
Awang, MohdShukrimi Bin
author_facet Khan, Ed Simor Khan Bin MorJapar
Thean, Charles Ang Poh
Zakaria, Zamzuri Bin
Awang, Mohamed Saufi Bin
Karupiah, Rajandra Kumar
Awang, MohdShukrimi Bin
author_sort Khan, Ed Simor Khan Bin MorJapar
collection PubMed
description INTRODUCTION: Spinal schwannoma can occur anywhere along the spinal cord but is predominantly seen in the cervical and thoracic region.It composes mainly of well-differentiated schwann cell and is benign in nature. It is typically seen in the peripheral nerves and is commonly associated with neurofibromatosis. Up to 80% of cases, spinal schwannoma is reported to be intradural in location and 15% of cases have both intradural and extradural components. Spinal schwannoma rarely causes conus medullaris syndrome. CASE REPORT: In this case series, all three female patients in their 4th and 5th decades of life presented with conus medullaris syndrome. Lower back pain, radiculopathy, lower limb weakness, and urinary incontinence are their main clinical presentation. Magnetic resonance imaging shows a well-defined intradural, extramedullary mass compressing onto the conus medullary region. These patients undergone microscopic assisted excision of the tumor and had remarkably good early outcome despite the advanced presentation of neurological deficit. CONCLUSION: Despite the late presentation with significant neurological deficit, surgical excision of spinal schwannomas carries a good prognosis postoperatively due to their benign nature and extramedullary location.
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spelling pubmed-74767002020-09-18 A Rare Presentation of Spinal Schwannoma Causing Conus Medullaris Syndrome: A Case Series on Surgical Outcome. Khan, Ed Simor Khan Bin MorJapar Thean, Charles Ang Poh Zakaria, Zamzuri Bin Awang, Mohamed Saufi Bin Karupiah, Rajandra Kumar Awang, MohdShukrimi Bin J Orthop Case Rep Case Report INTRODUCTION: Spinal schwannoma can occur anywhere along the spinal cord but is predominantly seen in the cervical and thoracic region.It composes mainly of well-differentiated schwann cell and is benign in nature. It is typically seen in the peripheral nerves and is commonly associated with neurofibromatosis. Up to 80% of cases, spinal schwannoma is reported to be intradural in location and 15% of cases have both intradural and extradural components. Spinal schwannoma rarely causes conus medullaris syndrome. CASE REPORT: In this case series, all three female patients in their 4th and 5th decades of life presented with conus medullaris syndrome. Lower back pain, radiculopathy, lower limb weakness, and urinary incontinence are their main clinical presentation. Magnetic resonance imaging shows a well-defined intradural, extramedullary mass compressing onto the conus medullary region. These patients undergone microscopic assisted excision of the tumor and had remarkably good early outcome despite the advanced presentation of neurological deficit. CONCLUSION: Despite the late presentation with significant neurological deficit, surgical excision of spinal schwannomas carries a good prognosis postoperatively due to their benign nature and extramedullary location. Indian Orthopaedic Research Group 2020 /pmc/articles/PMC7476700/ /pubmed/32953668 http://dx.doi.org/10.13107/jocr.2020.v10.i02.1718 Text en Copyright: © Indian Orthopaedic Research Group http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Khan, Ed Simor Khan Bin MorJapar
Thean, Charles Ang Poh
Zakaria, Zamzuri Bin
Awang, Mohamed Saufi Bin
Karupiah, Rajandra Kumar
Awang, MohdShukrimi Bin
A Rare Presentation of Spinal Schwannoma Causing Conus Medullaris Syndrome: A Case Series on Surgical Outcome.
title A Rare Presentation of Spinal Schwannoma Causing Conus Medullaris Syndrome: A Case Series on Surgical Outcome.
title_full A Rare Presentation of Spinal Schwannoma Causing Conus Medullaris Syndrome: A Case Series on Surgical Outcome.
title_fullStr A Rare Presentation of Spinal Schwannoma Causing Conus Medullaris Syndrome: A Case Series on Surgical Outcome.
title_full_unstemmed A Rare Presentation of Spinal Schwannoma Causing Conus Medullaris Syndrome: A Case Series on Surgical Outcome.
title_short A Rare Presentation of Spinal Schwannoma Causing Conus Medullaris Syndrome: A Case Series on Surgical Outcome.
title_sort rare presentation of spinal schwannoma causing conus medullaris syndrome: a case series on surgical outcome.
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476700/
https://www.ncbi.nlm.nih.gov/pubmed/32953668
http://dx.doi.org/10.13107/jocr.2020.v10.i02.1718
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