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Underground isoleucine biosynthesis pathways in E. coli

The promiscuous activities of enzymes provide fertile ground for the evolution of new metabolic pathways. Here, we systematically explore the ability of E. coli to harness underground metabolism to compensate for the deletion of an essential biosynthetic pathway. By deleting all threonine deaminases...

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Detalles Bibliográficos
Autores principales:	Cotton, Charles AR, Bernhardsgrütter, Iria, He, Hai, Burgener, Simon, Schulz, Luca, Paczia, Nicole, Dronsella, Beau, Erban, Alexander, Toman, Stepan, Dempfle, Marian, De Maria, Alberto, Kopka, Joachim, Lindner, Steffen N, Erb, Tobias J, Bar-Even, Arren
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2020
Materias:	Biochemistry and Chemical Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476758/ https://www.ncbi.nlm.nih.gov/pubmed/32831171 http://dx.doi.org/10.7554/eLife.54207

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