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Binding mechanism of the matrix domain of HIV-1 gag on lipid membranes

Specific protein-lipid interactions are critical for viral assembly. We present a molecular dynamics simulation study on the binding mechanism of the membrane targeting domain of HIV-1 Gag protein. The matrix (MA) domain drives Gag onto the plasma membrane through electrostatic interactions at its h...

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Detalles Bibliográficos
Autores principales:	Monje-Galvan, Viviana, Voth, Gregory A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2020
Materias:	Structural Biology and Molecular Biophysics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476761/ https://www.ncbi.nlm.nih.gov/pubmed/32808928 http://dx.doi.org/10.7554/eLife.58621

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