Activation of AMPK by Telmisartan Decreases Basal and PDGF-stimulated VSMC Proliferation via Inhibiting the mTOR/p70S6K Signaling Axis

BACKGROUND: Telmisartan, an angiotensin II type 1 receptor blocker (ARB), is widely used to treat hypertension by blocking the renin-angiotensin-aldosterone system. Although abnormal proliferation of vascular smooth muscle cells (VSMCs) is a well-established contributor to the development of various...

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Detalles Bibliográficos
Autores principales: Hwang, Yun-Jin, Park, Jung-Hyun, Cho, Du-Hyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476795/
https://www.ncbi.nlm.nih.gov/pubmed/32893519
http://dx.doi.org/10.3346/jkms.2020.35.e289

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476795/
https://www.ncbi.nlm.nih.gov/pubmed/32893519
http://dx.doi.org/10.3346/jkms.2020.35.e289

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