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Combined inhibition of JAK1/2 and DNMT1 by newly identified small-molecule compounds synergistically suppresses the survival and proliferation of cervical cancer cells

Despite substantial advances in treating cervical cancer (CC) with surgery, radiation and chemotherapy, patients with advanced CC still have poor prognosis and significantly variable clinical outcomes due to tumor recurrence and metastasis. Therefore, to develop more efficacious and specific treatme...

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Detalles Bibliográficos
Autores principales: She, Shiqi, Zhao, Yang, Kang, Bo, Chen, Cheng, Chen, Xinyu, Zhang, Xiaobing, Chen, Wenjie, Dan, Songsong, Wang, Hangxiang, Wang, Ying-Jie, Zhao, Jinhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476923/
https://www.ncbi.nlm.nih.gov/pubmed/32895373
http://dx.doi.org/10.1038/s41419-020-02934-8