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Transport properties in CFTR−/− knockout piglets suggest normal airway surface liquid pH and enhanced amiloride-sensitive Na(+) absorption

Previous analysis of CFTR-knockout (CFTR−/−) in piglets has provided important insights into the pathology of cystic fibrosis. However, controversies exist as to the true contribution of CFTR to the pH balance in airways and intestine. We therefore compared ion transport properties in newborn wild-t...

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Detalles Bibliográficos
Autores principales:	Benedetto, Roberta, Centeio, Raquel, Ousingsawat, Jiraporn, Schreiber, Rainer, Janda, Melanie, Kunzelmann, Karl
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2020
Materias:	Organ Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476968/ https://www.ncbi.nlm.nih.gov/pubmed/32712714 http://dx.doi.org/10.1007/s00424-020-02440-y

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