Dimethyl-2-oxoglutarate improves redox balance and mitochondrial function in muscle pericytes of individuals with diabetes mellitus

AIMS/HYPOTHESIS: Treatment of vascular complications of diabetes remains inadequate. We reported that muscle pericytes (MPs) from limb muscles of vascular patients with diabetes mellitus display elevated levels of oxidative stress causing a dysfunctional phenotype. Here, we investigated whether trea...

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Detalles Bibliográficos
Autores principales: Faulkner, Ashton, Tamiato, Anita, Cathery, William, Rampin, Andrea, Caravaggi, Carlo Maria, Jover, Eva, Allen, Steve, Mellor, Harry, Hauton, David, Heather, Lisa C., Spinetti, Gaia, Madeddu, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476972/
https://www.ncbi.nlm.nih.gov/pubmed/32728894
http://dx.doi.org/10.1007/s00125-020-05230-4

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