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Sodium New Houttuyfonate Inhibits Candida albicans Biofilm Formation by Inhibiting the Ras1-cAMP-Efg1 Pathway Revealed by RNA-seq

Here, we aim to investigate the antifungal effect and mechanism of action of sodium new houttuyfonate (SNH) against Candida albicans. Microdilution analysis results showed that SNH possesses potent inhibitory activity against C. albicans SC5314, with a MIC(80) of 256 μg/mL. Furthermore, we found tha...

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Detalles Bibliográficos
Autores principales: Wu, Jiadi, Wu, Daqiang, Zhao, Yeye, Si, Yuanqing, Mei, Longfei, Shao, Jing, Wang, Tianming, Yan, Guiming, Wang, Changzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477049/
https://www.ncbi.nlm.nih.gov/pubmed/32983053
http://dx.doi.org/10.3389/fmicb.2020.02075

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