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Sodium New Houttuyfonate Inhibits Candida albicans Biofilm Formation by Inhibiting the Ras1-cAMP-Efg1 Pathway Revealed by RNA-seq
Here, we aim to investigate the antifungal effect and mechanism of action of sodium new houttuyfonate (SNH) against Candida albicans. Microdilution analysis results showed that SNH possesses potent inhibitory activity against C. albicans SC5314, with a MIC(80) of 256 μg/mL. Furthermore, we found tha...
Autores principales: | Wu, Jiadi, Wu, Daqiang, Zhao, Yeye, Si, Yuanqing, Mei, Longfei, Shao, Jing, Wang, Tianming, Yan, Guiming, Wang, Changzhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477049/ https://www.ncbi.nlm.nih.gov/pubmed/32983053 http://dx.doi.org/10.3389/fmicb.2020.02075 |
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