Hypomyopathic Dermatomyositis with Refractory Dermatitis Treated by Low-dose IL-2

Hypomyopathic dermatomyositis (DM) presents with cutaneous lesions consistent with dermatomyositis but in the absence of clinically appreciable muscle weakness. The cutaneous manifestations are often refractory and more resistant to conventional therapy than concomitant muscle involvement. We presen...

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Detalles Bibliográficos
Autores principales: Miao, Miao, Li, Yuhui, Huang, Bo, He, Jing, Li, Zhanguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477052/
https://www.ncbi.nlm.nih.gov/pubmed/32648206
http://dx.doi.org/10.1007/s13555-020-00421-8
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author Miao, Miao
Li, Yuhui
Huang, Bo
He, Jing
Li, Zhanguo
author_facet Miao, Miao
Li, Yuhui
Huang, Bo
He, Jing
Li, Zhanguo
author_sort Miao, Miao
collection PubMed
description Hypomyopathic dermatomyositis (DM) presents with cutaneous lesions consistent with dermatomyositis but in the absence of clinically appreciable muscle weakness. The cutaneous manifestations are often refractory and more resistant to conventional therapy than concomitant muscle involvement. We present a 61-year-old hypomyopathic patient with DM who failed to respond to standard therapy but was successfully treated by low-dose interleukin-2 (IL-2) with no significant side effects. We conclude that low-dose IL-2 is a safe and effective treatment for hypomyopathic DM.
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spelling pubmed-74770522020-09-18 Hypomyopathic Dermatomyositis with Refractory Dermatitis Treated by Low-dose IL-2 Miao, Miao Li, Yuhui Huang, Bo He, Jing Li, Zhanguo Dermatol Ther (Heidelb) Case Report Hypomyopathic dermatomyositis (DM) presents with cutaneous lesions consistent with dermatomyositis but in the absence of clinically appreciable muscle weakness. The cutaneous manifestations are often refractory and more resistant to conventional therapy than concomitant muscle involvement. We present a 61-year-old hypomyopathic patient with DM who failed to respond to standard therapy but was successfully treated by low-dose interleukin-2 (IL-2) with no significant side effects. We conclude that low-dose IL-2 is a safe and effective treatment for hypomyopathic DM. Springer Healthcare 2020-07-09 /pmc/articles/PMC7477052/ /pubmed/32648206 http://dx.doi.org/10.1007/s13555-020-00421-8 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/.
spellingShingle Case Report
Miao, Miao
Li, Yuhui
Huang, Bo
He, Jing
Li, Zhanguo
Hypomyopathic Dermatomyositis with Refractory Dermatitis Treated by Low-dose IL-2
title Hypomyopathic Dermatomyositis with Refractory Dermatitis Treated by Low-dose IL-2
title_full Hypomyopathic Dermatomyositis with Refractory Dermatitis Treated by Low-dose IL-2
title_fullStr Hypomyopathic Dermatomyositis with Refractory Dermatitis Treated by Low-dose IL-2
title_full_unstemmed Hypomyopathic Dermatomyositis with Refractory Dermatitis Treated by Low-dose IL-2
title_short Hypomyopathic Dermatomyositis with Refractory Dermatitis Treated by Low-dose IL-2
title_sort hypomyopathic dermatomyositis with refractory dermatitis treated by low-dose il-2
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477052/
https://www.ncbi.nlm.nih.gov/pubmed/32648206
http://dx.doi.org/10.1007/s13555-020-00421-8
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