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An Optimization of AAV-82Q-Delivered Rat Model of Huntington’s Disease

OBJECTIVE: No optimum genetic rat Huntington model both neuropathological using an adeno-associated virus (AAV-2) vector vector has been reported to date. We investigated whether direct infection of an AAV2 encoding a fragment of mutant huntingtin (AV2-82Q) into the rat striatum was useful for optim...

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Detalles Bibliográficos
Autores principales:	So, Kyoung-Ha, Choi, Jai Ho, Islam, Jaisan, KC, Elina, Moon, Hyeong Cheol, Won, So Yoon, Kim, Hyong Kyu, Kim, Soochong, Hyun, Sang-Hwan, Park, Young Seok
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Neurosurgical Society 2020
Materias:	Laboratory Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477157/ https://www.ncbi.nlm.nih.gov/pubmed/32131152 http://dx.doi.org/10.3340/jkns.2019.0182

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