Purification of HCC-specific extracellular vesicles on nanosubstrates for early HCC detection by digital scoring

We report a covalent chemistry-based hepatocellular carcinoma (HCC)-specific extracellular vesicle (EV) purification system for early detection of HCC by performing digital scoring on the purified EVs. Earlier detection of HCC creates more opportunities for curative therapeutic interventions. EVs ar...

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Detalles Bibliográficos
Autores principales: Sun, Na, Lee, Yi-Te, Zhang, Ryan Y., Kao, Rueihung, Teng, Pai-Chi, Yang, Yingying, Yang, Peng, Wang, Jasmine J., Smalley, Matthew, Chen, Pin-Jung, Kim, Minhyung, Chou, Shih-Jie, Bao, Lirong, Wang, Jing, Zhang, Xinyue, Qi, Dongping, Palomique, Juvelyn, Nissen, Nicolas, Han, Steven-Huy B., Sadeghi, Saeed, Finn, Richard S., Saab, Sammy, Busuttil, Ronald W., Markovic, Daniela, Elashoff, David, Yu, Hsiao-hua, Li, Huiying, Heaney, Anthony P., Posadas, Edwin, You, Sungyong, Yang, Ju Dong, Pei, Renjun, Agopian, Vatche G., Tseng, Hsian-Rong, Zhu, Yazhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477161/
https://www.ncbi.nlm.nih.gov/pubmed/32895384
http://dx.doi.org/10.1038/s41467-020-18311-0

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