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Effects of Insulin-Like Growth Factor-I on the Expression of Atrogin-1/MAFbx in Chick Myotube Cultures

The expression of atrogin-1/MAFbx, a muscle-specific E3 ubiquitin ligase, is increased in catabolic conditions that result in muscle atrophy. The expression of atrogin-1/MAFbx mRNA is also decreased by the insulin-like growth factor-I (IGF-I) in mammalian skeletal muscle cell cultures. This study in...

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Detalles Bibliográficos
Autores principales: Nakashima, Kazuki, Ishida, Aiko, Shimamoto, Saki, Ijiri, Daichi, Ohtsuka, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japan Poultry Science Association 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477219/
https://www.ncbi.nlm.nih.gov/pubmed/32908433
http://dx.doi.org/10.2141/jpsa.0160141