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Knockout of EGFL6 by CRISPR/Cas9 Mediated Inhibition of Tumor Angiogenesis in Ovarian Cancer

Tumor angiogenesis plays an important role in the progression and metastasis of ovarian cancer. EGFL6 protein is highly expressed in ovarian cancer and has been proposed to play an important role in promoting tumor angiogenesis. Here, a CRISPR/Cas9 system was used to knockout the EGFL6 gene in the o...

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Detalles Bibliográficos
Autores principales: Zhu, Wenhui, Liu, Chunyan, Lu, Tongyi, Zhang, Yinmei, Zhang, Simin, Chen, Qi, Deng, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477343/
https://www.ncbi.nlm.nih.gov/pubmed/32983976
http://dx.doi.org/10.3389/fonc.2020.01451