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Work instability and associated factors among patients with rheumatoid arthritis in Greater Poland

OBJECTIVES: Rheumatoid arthritis (RA) affects patients’ capacity to work. The Rheumatoid Arthritis Work Instability Scale (RA-WIS) is a reliable method to measure work instability (WI) (1–3). We lack data on the relationship between RA and work instability among Polish patients. Our study aimed to a...

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Autores principales: Schmidt, Wiktor, Tąpolska, Małgorzata, Pawlak-Buś, Katarzyna, Owczarek, Magdalena, Leszczyński, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Narodowy Instytut Geriatrii, Reumatologii i Rehabilitacji w Warszawie 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477473/
https://www.ncbi.nlm.nih.gov/pubmed/32921827
http://dx.doi.org/10.5114/reum.2020.98432
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author Schmidt, Wiktor
Tąpolska, Małgorzata
Pawlak-Buś, Katarzyna
Owczarek, Magdalena
Leszczyński, Piotr
author_facet Schmidt, Wiktor
Tąpolska, Małgorzata
Pawlak-Buś, Katarzyna
Owczarek, Magdalena
Leszczyński, Piotr
author_sort Schmidt, Wiktor
collection PubMed
description OBJECTIVES: Rheumatoid arthritis (RA) affects patients’ capacity to work. The Rheumatoid Arthritis Work Instability Scale (RA-WIS) is a reliable method to measure work instability (WI) (1–3). We lack data on the relationship between RA and work instability among Polish patients. Our study aimed to assess WI and associated factors among patients with RA. MATERIAL AND METHODS: The authors conducted a multi-centre cross-sectional observational study. 315 patients from three rheumatology centres were enrolled and filled in questionnaires, including demographic and self-reported clinical data, RA-WIS, and the Health Assessment Questionnaire (HAQ). Swollen and tender joint counts (SJC, TJC) were assessed by the attending physician, and current erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) were collected. We excluded 41 patients due to an incorrectly filled in form and analysed questionnaires of 274 patients. DAS28 (Disease Activity Score in 28 joints) and DAS28-CRP were calculated. We performed statistical analysis with Statistica v. 13.3 using the Mann-Whitney U test, χ(2) test, and Spearman’s correlation. RESULTS: 140 (51%) patients were currently employed and their characteristics were analysed. In univariable analysis we identified the following risk factors for high risk WI: moderate-to-high disease activity (DAS28 ≥ 3.2 – OR 2.29, 95% CI 1.06–4.96, p = 0.033; DAS28-CRP ≥ 3.2 – OR 2.34, 95% CI 1.04–5.27, p = 0.038), ESR ≥ 30 mm/h in women and ≥ 20 mm/h in men (OR 2.65, 95% CI 1.20–5.89, p = 0.010), CRP ≥ 1 mg/dl (OR 4.02, 95% CI 1.78–9.10, p < 0.001), HAQ-DI > 1.0 (OR 2.23, 95% CI 1.04–4.81, p = 0.037) and at least moderate pain on the visual analogue scale (VAS p ≥ 4.5 cm – OR 5.31, 95% CI 2.36–11.96, p < 0.001). Correlations were moderate between RA-WIS and VASp (RS = 0.59, p < 0.001) and HAQ-DI (RS = 0.52, p < 0.001) but weak with disease activity indices (DAS28 [RS = 0.31, p < 0.001]; DAS28-CRP [RS = 0.28, p < 0.001]). CONCLUSIONS: Pain and disability are the main factors strongly associated with work instability among patients with RA.
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spelling pubmed-74774732020-09-11 Work instability and associated factors among patients with rheumatoid arthritis in Greater Poland Schmidt, Wiktor Tąpolska, Małgorzata Pawlak-Buś, Katarzyna Owczarek, Magdalena Leszczyński, Piotr Reumatologia Original Paper OBJECTIVES: Rheumatoid arthritis (RA) affects patients’ capacity to work. The Rheumatoid Arthritis Work Instability Scale (RA-WIS) is a reliable method to measure work instability (WI) (1–3). We lack data on the relationship between RA and work instability among Polish patients. Our study aimed to assess WI and associated factors among patients with RA. MATERIAL AND METHODS: The authors conducted a multi-centre cross-sectional observational study. 315 patients from three rheumatology centres were enrolled and filled in questionnaires, including demographic and self-reported clinical data, RA-WIS, and the Health Assessment Questionnaire (HAQ). Swollen and tender joint counts (SJC, TJC) were assessed by the attending physician, and current erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) were collected. We excluded 41 patients due to an incorrectly filled in form and analysed questionnaires of 274 patients. DAS28 (Disease Activity Score in 28 joints) and DAS28-CRP were calculated. We performed statistical analysis with Statistica v. 13.3 using the Mann-Whitney U test, χ(2) test, and Spearman’s correlation. RESULTS: 140 (51%) patients were currently employed and their characteristics were analysed. In univariable analysis we identified the following risk factors for high risk WI: moderate-to-high disease activity (DAS28 ≥ 3.2 – OR 2.29, 95% CI 1.06–4.96, p = 0.033; DAS28-CRP ≥ 3.2 – OR 2.34, 95% CI 1.04–5.27, p = 0.038), ESR ≥ 30 mm/h in women and ≥ 20 mm/h in men (OR 2.65, 95% CI 1.20–5.89, p = 0.010), CRP ≥ 1 mg/dl (OR 4.02, 95% CI 1.78–9.10, p < 0.001), HAQ-DI > 1.0 (OR 2.23, 95% CI 1.04–4.81, p = 0.037) and at least moderate pain on the visual analogue scale (VAS p ≥ 4.5 cm – OR 5.31, 95% CI 2.36–11.96, p < 0.001). Correlations were moderate between RA-WIS and VASp (RS = 0.59, p < 0.001) and HAQ-DI (RS = 0.52, p < 0.001) but weak with disease activity indices (DAS28 [RS = 0.31, p < 0.001]; DAS28-CRP [RS = 0.28, p < 0.001]). CONCLUSIONS: Pain and disability are the main factors strongly associated with work instability among patients with RA. Narodowy Instytut Geriatrii, Reumatologii i Rehabilitacji w Warszawie 2020-08-31 2020 /pmc/articles/PMC7477473/ /pubmed/32921827 http://dx.doi.org/10.5114/reum.2020.98432 Text en Copyright © 2020 Narodowy Instytut Geriatrii, Reumatologii i Rehabilitacji w Warszawie http://creativecommons.org/licenses/by-nc-sa/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0). License (http://creativecommons.org/licenses/by-nc-sa/4.0/)
spellingShingle Original Paper
Schmidt, Wiktor
Tąpolska, Małgorzata
Pawlak-Buś, Katarzyna
Owczarek, Magdalena
Leszczyński, Piotr
Work instability and associated factors among patients with rheumatoid arthritis in Greater Poland
title Work instability and associated factors among patients with rheumatoid arthritis in Greater Poland
title_full Work instability and associated factors among patients with rheumatoid arthritis in Greater Poland
title_fullStr Work instability and associated factors among patients with rheumatoid arthritis in Greater Poland
title_full_unstemmed Work instability and associated factors among patients with rheumatoid arthritis in Greater Poland
title_short Work instability and associated factors among patients with rheumatoid arthritis in Greater Poland
title_sort work instability and associated factors among patients with rheumatoid arthritis in greater poland
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477473/
https://www.ncbi.nlm.nih.gov/pubmed/32921827
http://dx.doi.org/10.5114/reum.2020.98432
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