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What can we learn from the islet of Joslin Medalists?

This commentary refers to the recent study of Joslin Medalists that showed evidence of residual endocrine cells still functioning in response to glucose stimuli. Islet pathology showed the ongoing remodeling influenced by autoimmune attack and glucose toxicity. The results showed the presence of fun...

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Detalles Bibliográficos
Autor principal: Yagihashi, Soroku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477497/
https://www.ncbi.nlm.nih.gov/pubmed/32343033
http://dx.doi.org/10.1111/jdi.13283
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author Yagihashi, Soroku
author_facet Yagihashi, Soroku
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description This commentary refers to the recent study of Joslin Medalists that showed evidence of residual endocrine cells still functioning in response to glucose stimuli. Islet pathology showed the ongoing remodeling influenced by autoimmune attack and glucose toxicity. The results showed the presence of functional endocrine cells that contribute to the longevity of patients with type 1 diabetes.[Image: see text]
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spelling pubmed-74774972020-09-11 What can we learn from the islet of Joslin Medalists? Yagihashi, Soroku J Diabetes Investig Commentaries This commentary refers to the recent study of Joslin Medalists that showed evidence of residual endocrine cells still functioning in response to glucose stimuli. Islet pathology showed the ongoing remodeling influenced by autoimmune attack and glucose toxicity. The results showed the presence of functional endocrine cells that contribute to the longevity of patients with type 1 diabetes.[Image: see text] John Wiley and Sons Inc. 2020-06-13 2020-09 /pmc/articles/PMC7477497/ /pubmed/32343033 http://dx.doi.org/10.1111/jdi.13283 Text en © 2020 The Author. Journal of Diabetes Investigation published by Asian Association for the Study of Diabetes (AASD) and John Wiley & Sons Australia, Ltd This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Commentaries
Yagihashi, Soroku
What can we learn from the islet of Joslin Medalists?
title What can we learn from the islet of Joslin Medalists?
title_full What can we learn from the islet of Joslin Medalists?
title_fullStr What can we learn from the islet of Joslin Medalists?
title_full_unstemmed What can we learn from the islet of Joslin Medalists?
title_short What can we learn from the islet of Joslin Medalists?
title_sort what can we learn from the islet of joslin medalists?
topic Commentaries
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477497/
https://www.ncbi.nlm.nih.gov/pubmed/32343033
http://dx.doi.org/10.1111/jdi.13283
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