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Iron Deficiency Anemia in Pregnancy: Novel Approaches for an Old Problem
Iron needs increase exponentially during pregnancy to meet the increased demands of the fetoplacental unit, to expand maternal erythrocyte mass, and to compensate for iron loss at delivery. In more than 80% of countries in the world, the prevalence of anemia in pregnancy is > 20% and could be con...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
OMJ
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477519/ https://www.ncbi.nlm.nih.gov/pubmed/32953141 http://dx.doi.org/10.5001/omj.2020.108 |
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author | Garzon, Simone Cacciato, Patrizia Maria Certelli, Camilla Salvaggio, Calogero Magliarditi, Maria Rizzo, Gianluca |
author_facet | Garzon, Simone Cacciato, Patrizia Maria Certelli, Camilla Salvaggio, Calogero Magliarditi, Maria Rizzo, Gianluca |
author_sort | Garzon, Simone |
collection | PubMed |
description | Iron needs increase exponentially during pregnancy to meet the increased demands of the fetoplacental unit, to expand maternal erythrocyte mass, and to compensate for iron loss at delivery. In more than 80% of countries in the world, the prevalence of anemia in pregnancy is > 20% and could be considered a major public health problem. The global prevalence of anemia in pregnancy is estimated to be approximately 41.8%. Undiagnosed and untreated iron deficiency anemia (IDA) can have a great impact on maternal and fetal health. Indeed, chronic iron deficiency can affect the general wellbeing of the mother and leads to fatigue and reduced working capacity. Given the significant adverse impact on maternal-fetal outcomes, early recognition and treatment of this clinical condition is fundamental. Therefore, the laboratory assays are recommended from the first trimester to evaluate the iron status. Oral iron supplementation is the first line of treatment in cases of mild anemia. However, considering the numerous gastrointestinal side effects that often lead to poor compliance, other therapeutic strategies should be evaluated. This review aims to provide an overview of the current evidence about the management of IDA in pregnancy and available treatment options. |
format | Online Article Text |
id | pubmed-7477519 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | OMJ |
record_format | MEDLINE/PubMed |
spelling | pubmed-74775192020-09-18 Iron Deficiency Anemia in Pregnancy: Novel Approaches for an Old Problem Garzon, Simone Cacciato, Patrizia Maria Certelli, Camilla Salvaggio, Calogero Magliarditi, Maria Rizzo, Gianluca Oman Med J Review Article Iron needs increase exponentially during pregnancy to meet the increased demands of the fetoplacental unit, to expand maternal erythrocyte mass, and to compensate for iron loss at delivery. In more than 80% of countries in the world, the prevalence of anemia in pregnancy is > 20% and could be considered a major public health problem. The global prevalence of anemia in pregnancy is estimated to be approximately 41.8%. Undiagnosed and untreated iron deficiency anemia (IDA) can have a great impact on maternal and fetal health. Indeed, chronic iron deficiency can affect the general wellbeing of the mother and leads to fatigue and reduced working capacity. Given the significant adverse impact on maternal-fetal outcomes, early recognition and treatment of this clinical condition is fundamental. Therefore, the laboratory assays are recommended from the first trimester to evaluate the iron status. Oral iron supplementation is the first line of treatment in cases of mild anemia. However, considering the numerous gastrointestinal side effects that often lead to poor compliance, other therapeutic strategies should be evaluated. This review aims to provide an overview of the current evidence about the management of IDA in pregnancy and available treatment options. OMJ 2020-09-01 /pmc/articles/PMC7477519/ /pubmed/32953141 http://dx.doi.org/10.5001/omj.2020.108 Text en The OMJ is Published Bimonthly and Copyrighted 2020 by the OMSB. This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial (CC BY-NC) 4.0 License. http://creativecommons.org/licenses/by-nc/4.0/ |
spellingShingle | Review Article Garzon, Simone Cacciato, Patrizia Maria Certelli, Camilla Salvaggio, Calogero Magliarditi, Maria Rizzo, Gianluca Iron Deficiency Anemia in Pregnancy: Novel Approaches for an Old Problem |
title | Iron Deficiency Anemia in Pregnancy: Novel Approaches for an Old Problem |
title_full | Iron Deficiency Anemia in Pregnancy: Novel Approaches for an Old Problem |
title_fullStr | Iron Deficiency Anemia in Pregnancy: Novel Approaches for an Old Problem |
title_full_unstemmed | Iron Deficiency Anemia in Pregnancy: Novel Approaches for an Old Problem |
title_short | Iron Deficiency Anemia in Pregnancy: Novel Approaches for an Old Problem |
title_sort | iron deficiency anemia in pregnancy: novel approaches for an old problem |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477519/ https://www.ncbi.nlm.nih.gov/pubmed/32953141 http://dx.doi.org/10.5001/omj.2020.108 |
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